The transfer of maternal antibodies and dynamics of maternal and natural infection-induced antibodies against coxsackievirus A16 in Chinese children 0–13 years of age: a longitudinal cohort study

The transfer of maternal antibodies and dynamics of maternal and natural infection-induced antibodies against coxsackievirus A16 in Chinese children 0–13 years of age: a longitudinal cohort study

Abstract Background A major hand-foot-and-mouth disease (HFMD) pathogen, coxsackievirus A16 (CVA16), has predominated in several of the last 10 years and caused the largest number of HFMD outbreaks between 2011 and 2018 in China. We evaluated the efficacy of maternal anti-CVA16 antibody transfer via...

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Bibliographic Details
Main Authors: Jiaxin Zhou, Yonghong Zhou, Kaiwei Luo, Qiaohong Liao, Wen Zheng, Hui Gong, Huilin Shi, Shanlu Zhao, Kai Wang, Qi Qiu, Bingbing Dai, Lingshuang Ren, Lili Wang, Lidong Gao, Meng Xu, Nuolan Liu, Wanying Lu, Nan Zheng, Xinhua Chen, Zhiyuan Chen, Juan Yang, Simon Cauchemez, Hongjie Yu
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medicine
Subjects:
Coxsackievirus A16 (CVA16)
Transplacental transfer
Maternal antibody
Natural infection
Antibody kinetics
Online Access:https://doi.org/10.1186/s12916-022-02604-w

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