Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trial
Abstract Background Ultrasound-guided intertruncal approach (IA) has been proposed to be an alternative and promising approach to the supraclavicular block (SCB), in which double injection (DI) of local anesthetics (LA) is sequentially administered between intertruncal planes. We would like to apply...
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BMC
2022-04-01
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| Online Access: | https://doi.org/10.1186/s13063-022-06260-6 |
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| author | Quehua Luo Huiying Liu Longjiao Deng Lidan Nong Haifeng Li Yujing Cai Junyi Zheng Haihua Shu Weifeng Yao Jianxing Zhang |
| author_facet | Quehua Luo Huiying Liu Longjiao Deng Lidan Nong Haifeng Li Yujing Cai Junyi Zheng Haihua Shu Weifeng Yao Jianxing Zhang |
| author_sort | Quehua Luo |
| collection | DOAJ |
| description | Abstract Background Ultrasound-guided intertruncal approach (IA) has been proposed to be an alternative and promising approach to the supraclavicular block (SCB), in which double injection (DI) of local anesthetics (LA) is sequentially administered between intertruncal planes. We would like to apply a refined injection technique, named triple injection (TI) technique, based on the 3 separate compartments visualized by ultrasound. The aim of this study is to compare the percentage of patients with complete sensory blockade at 20 min of DI vs TI technique, when they are applied in patients undergoing upper limb arteriovenous access surgery. Methods This study is a prospective parallel-group randomized controlled trial. A total of 86 end-stage renal disease patients will be randomly allocated to receive IA-SCB using either DI or TI technique with identical LA (0.5% ropivacaine 24 mL). The primary outcome is the percentage of patients with complete sensory blockade of all 4 terminal nerves (median, ulnar, radial, and musculocutaneous nerves) of the brachial plexus measured at 20 min after injection. The secondary outcomes will consist of the sensory or motor blockade of all individual nerves, onset times, performance time, diaphragmatic paralysis, surgical anesthesia, and adverse events. Discussion It is expected that ultrasound-guided IA-SCB with the TI technique results in better block dynamic in patients undergoing upper limb arteriovenous access surgery. Trial registration Chinese Clinical Trial Registry ChiCTR2100045075 . |
| first_indexed | 2024-12-10T03:28:42Z |
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| id | doaj.art-2eed306d074b4c148466cd17ddb26c5c |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-12-10T03:28:42Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
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| series | Trials |
| spelling | doaj.art-2eed306d074b4c148466cd17ddb26c5c2022-12-22T02:03:52ZengBMCTrials1745-62152022-04-012311910.1186/s13063-022-06260-6Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trialQuehua Luo0Huiying Liu1Longjiao Deng2Lidan Nong3Haifeng Li4Yujing Cai5Junyi Zheng6Haihua Shu7Weifeng Yao8Jianxing Zhang9Department of Anesthesiology, Guangdong Provincial People’s Hospital, and Guangdong Academy of Medical SciencesDepartment of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese MedicineDepartment of Anesthesiology, Guangdong Provincial People’s Hospital, and Guangdong Academy of Medical SciencesDepartment of Anesthesiology, Guangdong Provincial People’s Hospital, and Guangdong Academy of Medical SciencesDepartment of Anesthesiology, Guangdong Provincial People’s Hospital, and Guangdong Academy of Medical SciencesDepartment of Anesthesiology, Guangdong Provincial People’s Hospital, and Guangdong Academy of Medical SciencesDepartment of Anesthesiology, the First Affiliated Hospital of Guangzhou University of Chinese MedicineDepartment of Anesthesiology, Guangdong Provincial People’s Hospital, and Guangdong Academy of Medical SciencesDepartment of Anesthesiology, the Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, Guangdong Provincial People’s Hospital, and Guangdong Academy of Medical SciencesAbstract Background Ultrasound-guided intertruncal approach (IA) has been proposed to be an alternative and promising approach to the supraclavicular block (SCB), in which double injection (DI) of local anesthetics (LA) is sequentially administered between intertruncal planes. We would like to apply a refined injection technique, named triple injection (TI) technique, based on the 3 separate compartments visualized by ultrasound. The aim of this study is to compare the percentage of patients with complete sensory blockade at 20 min of DI vs TI technique, when they are applied in patients undergoing upper limb arteriovenous access surgery. Methods This study is a prospective parallel-group randomized controlled trial. A total of 86 end-stage renal disease patients will be randomly allocated to receive IA-SCB using either DI or TI technique with identical LA (0.5% ropivacaine 24 mL). The primary outcome is the percentage of patients with complete sensory blockade of all 4 terminal nerves (median, ulnar, radial, and musculocutaneous nerves) of the brachial plexus measured at 20 min after injection. The secondary outcomes will consist of the sensory or motor blockade of all individual nerves, onset times, performance time, diaphragmatic paralysis, surgical anesthesia, and adverse events. Discussion It is expected that ultrasound-guided IA-SCB with the TI technique results in better block dynamic in patients undergoing upper limb arteriovenous access surgery. Trial registration Chinese Clinical Trial Registry ChiCTR2100045075 .https://doi.org/10.1186/s13063-022-06260-6Intertruncal approachUltrasoundBrachial plexusSupraclavicular blockInjection technique |
| spellingShingle | Quehua Luo Huiying Liu Longjiao Deng Lidan Nong Haifeng Li Yujing Cai Junyi Zheng Haihua Shu Weifeng Yao Jianxing Zhang Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trial Trials Intertruncal approach Ultrasound Brachial plexus Supraclavicular block Injection technique |
| title | Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trial |
| title_full | Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trial |
| title_fullStr | Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trial |
| title_full_unstemmed | Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trial |
| title_short | Effects of double vs triple injection on block dynamics for ultrasound-guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery: study protocol for a double-blinded, randomized controlled trial |
| title_sort | effects of double vs triple injection on block dynamics for ultrasound guided intertruncal approach to the supraclavicular brachial plexus block in patients undergoing upper limb arteriovenous access surgery study protocol for a double blinded randomized controlled trial |
| topic | Intertruncal approach Ultrasound Brachial plexus Supraclavicular block Injection technique |
| url | https://doi.org/10.1186/s13063-022-06260-6 |
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