The Fine Tuning of Drp1-Dependent Mitochondrial Remodeling and Autophagy Controls Neuronal Differentiation

The Fine Tuning of Drp1-Dependent Mitochondrial Remodeling and Autophagy Controls Neuronal Differentiation

Mitochondria play a critical role in neuronal function and neurodegenerative disorders, including Alzheimer’s, Parkinson’s and Huntington diseases and amyotrophic lateral sclerosis, that show mitochondrial dysfunctions associated with excessive fission and increased levels of the fission protein dyn...

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Bibliographic Details
Main Authors: Chiara Vantaggiato, Marianna Castelli, Matteo Giovarelli, Genny Orso, Maria Teresa Bassi, Emilio Clementi, Clara De Palma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Drp1
neuronal differentiation
mitochondrial remodeling
autophagy
mitochondrial fission
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00120/full

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