State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans

A randomized study of the state of stiffness parameters arteries wall (CAVI — cardio-ankle vascular index), AI (augmentation index) PEP (duration of the voltage of the left ventricle) using «VaSera-1000» («Fukuda Denshi», Japan) in primary hypertension patients (80) not treated with systemic antihyp...

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Main Authors: V. P. Mikhin, U. A. Boldyreva, M. A. Chernyatina, N. I. Gromnatsky
Format: Article
Language:Russian
Published: SINAPS LLC 2015-10-01
Series:Архивъ внутренней медицины
Subjects:
Online Access:https://www.medarhive.ru/jour/article/view/454
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author V. P. Mikhin
U. A. Boldyreva
M. A. Chernyatina
N. I. Gromnatsky
author_facet V. P. Mikhin
U. A. Boldyreva
M. A. Chernyatina
N. I. Gromnatsky
author_sort V. P. Mikhin
collection DOAJ
description A randomized study of the state of stiffness parameters arteries wall (CAVI — cardio-ankle vascular index), AI (augmentation index) PEP (duration of the voltage of the left ventricle) using «VaSera-1000» («Fukuda Denshi», Japan) in primary hypertension patients (80) not treated with systemic antihypertensive therapy. The effect of long-term (3 months) was be marketed. Losartan combined with Mexicor 300mg/day or mildronate 1000 mg/day for the specified parameters. It sets the initial reduction the properties of the arterial wall in patients with hypertension, in contrast to healthy individuals. Mexicor or mildronat accompanied by improvement east-cal properties of the arterial wall, reducing CAVI and AI in 3 months on 9.4% and 8.9%, 14.9% and 15.4%, respectively. In the control group-term change CAVI and AI no. Mexicor led to a more pronounced increase in PEP, than mildronate, respectively, on 23.7% and 18.9%. Losartan monotherapy results in a less pronounced decrease in the stiffness of the vessel wall.
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spelling doaj.art-2ef46dfa165c409cb69894db1694c2602023-03-13T07:12:06ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642015-10-0105404410.20514/2226-6704-2015-0-5-15464State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartansV. P. Mikhin0U. A. Boldyreva1M. A. Chernyatina2N. I. Gromnatsky3Курский государственный медицинский университетКурский государственный медицинский университетКурский государственный медицинский университетКурский государственный медицинский университетA randomized study of the state of stiffness parameters arteries wall (CAVI — cardio-ankle vascular index), AI (augmentation index) PEP (duration of the voltage of the left ventricle) using «VaSera-1000» («Fukuda Denshi», Japan) in primary hypertension patients (80) not treated with systemic antihypertensive therapy. The effect of long-term (3 months) was be marketed. Losartan combined with Mexicor 300mg/day or mildronate 1000 mg/day for the specified parameters. It sets the initial reduction the properties of the arterial wall in patients with hypertension, in contrast to healthy individuals. Mexicor or mildronat accompanied by improvement east-cal properties of the arterial wall, reducing CAVI and AI in 3 months on 9.4% and 8.9%, 14.9% and 15.4%, respectively. In the control group-term change CAVI and AI no. Mexicor led to a more pronounced increase in PEP, than mildronate, respectively, on 23.7% and 18.9%. Losartan monotherapy results in a less pronounced decrease in the stiffness of the vessel wall.https://www.medarhive.ru/jour/article/view/454артериальная гипертонияжесткость сосудистой стенкимексикормилдронат
spellingShingle V. P. Mikhin
U. A. Boldyreva
M. A. Chernyatina
N. I. Gromnatsky
State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
Архивъ внутренней медицины
артериальная гипертония
жесткость сосудистой стенки
мексикор
милдронат
title State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
title_full State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
title_fullStr State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
title_full_unstemmed State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
title_short State stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
title_sort state stiffness parameters of the vascular wall in hypertensive patients complex therapy cytoprotector and sartans
topic артериальная гипертония
жесткость сосудистой стенки
мексикор
милдронат
url https://www.medarhive.ru/jour/article/view/454
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AT machernyatina statestiffnessparametersofthevascularwallinhypertensivepatientscomplextherapycytoprotectorandsartans
AT nigromnatsky statestiffnessparametersofthevascularwallinhypertensivepatientscomplextherapycytoprotectorandsartans