ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway

ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway

Abstract Hair follicle-derived mesenchymal stem cells (HF-MSCs) show considerable therapeutic potential for liver cirrhosis (LC). To improve the effectiveness of naïve HF-MSC treatments on LC, we used bioinformatic tools to identify an exogenous gene targeting HSCs among the differentially expressed...

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Bibliographic Details
Main Authors: Qi Liu, Chengqian Lv, Qianqian Huang, Lei Zhao, Xiaoli Sun, Dandan Ning, Jingyang Liu, Yanan Jiang, Shizhu Jin
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00846-4

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