A New Low-Energy Proton Irradiation Facility to Unveil the Mechanistic Basis of the Proton-Boron Capture Therapy Approach

A New Low-Energy Proton Irradiation Facility to Unveil the Mechanistic Basis of the Proton-Boron Capture Therapy Approach

Protontherapy (PT) is a fast-growing cancer therapy modality thanks to much-improved normal tissue sparing granted by the charged particles’ inverted dose-depth profile. Protons, however, exhibit a low biological effectiveness at clinically relevant energies. To enhance PT efficacy and counteract ca...

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Bibliographic Details
Main Authors: Valerio Ricciardi, Pavel Bláha, Raffaele Buompane, Giuseppina Crescente, Giacomo Cuttone, Lucio Gialanella, Katarina Michaličková, Severina Pacifico, Giuseppe Porzio, Lorenzo Manti
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Applied Sciences
Subjects:
protontherapy
Proton-Boron Capture Therapy (PBCT)
Proton-Boron Fusion-Enhanced Protontherapy (PBFEPT)
BSH
low-energy protons
alpha particles
Online Access:https://www.mdpi.com/2076-3417/11/24/11986

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