Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General Anesthesia
Background: This study aimed to compare the effects of remifentanyl-propofol and remifentasnyl-isoflurane on hemodynamic variables, blood gases, and blood glucose among patients under general anesthesia. Methods: In a clinical trial study, 110 patients under neurosurgeries with general anesthesia w...
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| Format: | Article |
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Isfahan University of Medical Sciences
2017-05-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/7289 |
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| author | Mohammadreza Safavi Azim Honarmand Rokhsareh Hajimohammady |
| author_facet | Mohammadreza Safavi Azim Honarmand Rokhsareh Hajimohammady |
| author_sort | Mohammadreza Safavi |
| collection | DOAJ |
| description | Background: This study aimed to compare the effects of remifentanyl-propofol and remifentasnyl-isoflurane on hemodynamic variables, blood gases, and blood glucose among patients under general anesthesia.
Methods: In a clinical trial study, 110 patients under neurosurgeries with general anesthesia were selected and randomly divided in to two groups. Continuing of anesthesia in the first and second groups was done by remifentanyl-propofol and remifentasnyl-isoflurane, respectively. The changes of hemodynamic variables, blood gases, and blood glucose were compared between the two groups.
Findings: The mean blood glucose level in the first hour was significantly more in remifentanyl-propofol group (114.3 ± 44.5 mg/dl) compared to remifentasnyl-isoflurane group (94.7 ± 26.9 mg/dl) (P = 0.006); the mean blood glucose levels in the second and third hours were significantly more in remifentanyl-propofol group, too (P < 0.001 for both). In addition, mean blood pressure levels was significantly more in remifentanyl-propofol group (P < 0.050 for all); but blood gases analysis did not show any statistically difference between the groups.
Conclusion: Using remifentanyl + isoflurane in patients underwent neurosurgery with general anesthesia led to better blood glucose and blood pressure levels and using this compound is recommended. |
| first_indexed | 2024-03-12T08:18:38Z |
| format | Article |
| id | doaj.art-2efaa66038fc4eb9a246a8d6bac93fb2 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T08:18:38Z |
| publishDate | 2017-05-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-2efaa66038fc4eb9a246a8d6bac93fb22023-09-02T18:38:05ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2017-05-01354211931992459Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General AnesthesiaMohammadreza Safavi0Azim Honarmand1Rokhsareh HajimohammadyProfessor, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, IranStudent of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranBackground: This study aimed to compare the effects of remifentanyl-propofol and remifentasnyl-isoflurane on hemodynamic variables, blood gases, and blood glucose among patients under general anesthesia. Methods: In a clinical trial study, 110 patients under neurosurgeries with general anesthesia were selected and randomly divided in to two groups. Continuing of anesthesia in the first and second groups was done by remifentanyl-propofol and remifentasnyl-isoflurane, respectively. The changes of hemodynamic variables, blood gases, and blood glucose were compared between the two groups. Findings: The mean blood glucose level in the first hour was significantly more in remifentanyl-propofol group (114.3 ± 44.5 mg/dl) compared to remifentasnyl-isoflurane group (94.7 ± 26.9 mg/dl) (P = 0.006); the mean blood glucose levels in the second and third hours were significantly more in remifentanyl-propofol group, too (P < 0.001 for both). In addition, mean blood pressure levels was significantly more in remifentanyl-propofol group (P < 0.050 for all); but blood gases analysis did not show any statistically difference between the groups. Conclusion: Using remifentanyl + isoflurane in patients underwent neurosurgery with general anesthesia led to better blood glucose and blood pressure levels and using this compound is recommended.http://jims.mui.ac.ir/index.php/jims/article/view/7289AnesthesiaGeneralHemodynamicBlood gas analysis |
| spellingShingle | Mohammadreza Safavi Azim Honarmand Rokhsareh Hajimohammady Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General Anesthesia مجله دانشکده پزشکی اصفهان Anesthesia General Hemodynamic Blood gas analysis |
| title | Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General Anesthesia |
| title_full | Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General Anesthesia |
| title_fullStr | Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General Anesthesia |
| title_full_unstemmed | Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General Anesthesia |
| title_short | Comparison of the Effects of Remifentanyl-Propofol and Remifentasnyl-Isoflurane on Hemodynamic Variables, Blood Gases, and Blood Glucose among Patients under General Anesthesia |
| title_sort | comparison of the effects of remifentanyl propofol and remifentasnyl isoflurane on hemodynamic variables blood gases and blood glucose among patients under general anesthesia |
| topic | Anesthesia General Hemodynamic Blood gas analysis |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/7289 |
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