Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areas
Summary: Visual perceptual experience induces persistent 4–8 Hz oscillations in the mouse primary visual cortex (V1), encoding visual familiarity. Recent studies suggest that higher-order visual areas (HVAs) are functionally specialized and segregated into information streams processing distinct vis...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124723014948 |
| _version_ | 1827631691207802880 |
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| author | Yu Tang Catherine Gervais Rylann Moffitt Sanghamitra Nareddula Michael Zimmermann Yididiya Y. Nadew Christopher J. Quinn Violeta Saldarriaga Paige Edens Alexander A. Chubykin |
| author_facet | Yu Tang Catherine Gervais Rylann Moffitt Sanghamitra Nareddula Michael Zimmermann Yididiya Y. Nadew Christopher J. Quinn Violeta Saldarriaga Paige Edens Alexander A. Chubykin |
| author_sort | Yu Tang |
| collection | DOAJ |
| description | Summary: Visual perceptual experience induces persistent 4–8 Hz oscillations in the mouse primary visual cortex (V1), encoding visual familiarity. Recent studies suggest that higher-order visual areas (HVAs) are functionally specialized and segregated into information streams processing distinct visual features. However, whether visual memories are processed and stored within the distinct streams is not understood. We report here that V1 and lateromedial (LM), but not V1 and anterolateral, become more phase synchronized in 4–8 Hz after the entrainment of visual stimulus that maximally induces responses in LM. Directed information analysis reveals changes in the top-down functional connectivity between V1 and HVAs. Optogenetic inactivation of LM reduces post-stimulus oscillation peaks in V1 and impairs visual discrimination behavior. Our results demonstrate that 4–8 Hz familiarity-evoked oscillations are specific for the distinct visual features and are present in the corresponding HVAs, where they may be used for the inter-areal communication with V1 during memory-related behaviors. |
| first_indexed | 2024-03-09T14:25:36Z |
| format | Article |
| id | doaj.art-2efae8dbd330468e8f51fb324baf61ab |
| institution | Directory Open Access Journal |
| issn | 2211-1247 |
| language | English |
| last_indexed | 2024-03-09T14:25:36Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj.art-2efae8dbd330468e8f51fb324baf61ab2023-11-28T07:25:49ZengElsevierCell Reports2211-12472023-12-014212113482Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areasYu Tang0Catherine Gervais1Rylann Moffitt2Sanghamitra Nareddula3Michael Zimmermann4Yididiya Y. Nadew5Christopher J. Quinn6Violeta Saldarriaga7Paige Edens8Alexander A. Chubykin9Department of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USADepartment of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USADepartment of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USADepartment of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USADepartment of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USADepartment of Computer Sciences, Iowa State University, Ames, IA 50011, USADepartment of Computer Sciences, Iowa State University, Ames, IA 50011, USADepartment of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USADepartment of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USADepartment of Biological Sciences, Purdue Institute for Integrative Neuroscience, Purdue Autism Research Center, Purdue University, West Lafayette, IN 47907, USA; Corresponding authorSummary: Visual perceptual experience induces persistent 4–8 Hz oscillations in the mouse primary visual cortex (V1), encoding visual familiarity. Recent studies suggest that higher-order visual areas (HVAs) are functionally specialized and segregated into information streams processing distinct visual features. However, whether visual memories are processed and stored within the distinct streams is not understood. We report here that V1 and lateromedial (LM), but not V1 and anterolateral, become more phase synchronized in 4–8 Hz after the entrainment of visual stimulus that maximally induces responses in LM. Directed information analysis reveals changes in the top-down functional connectivity between V1 and HVAs. Optogenetic inactivation of LM reduces post-stimulus oscillation peaks in V1 and impairs visual discrimination behavior. Our results demonstrate that 4–8 Hz familiarity-evoked oscillations are specific for the distinct visual features and are present in the corresponding HVAs, where they may be used for the inter-areal communication with V1 during memory-related behaviors.http://www.sciencedirect.com/science/article/pii/S2211124723014948CP: Neuroscience |
| spellingShingle | Yu Tang Catherine Gervais Rylann Moffitt Sanghamitra Nareddula Michael Zimmermann Yididiya Y. Nadew Christopher J. Quinn Violeta Saldarriaga Paige Edens Alexander A. Chubykin Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areas Cell Reports CP: Neuroscience |
| title | Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areas |
| title_full | Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areas |
| title_fullStr | Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areas |
| title_full_unstemmed | Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areas |
| title_short | Visual experience induces 4–8 Hz synchrony between V1 and higher-order visual areas |
| title_sort | visual experience induces 4 8 hz synchrony between v1 and higher order visual areas |
| topic | CP: Neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2211124723014948 |
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