Integrated bioinformatics analysis reveals that EZH2-rich domains promote transcriptional repression in cervical cancer

Integrated bioinformatics analysis reveals that EZH2-rich domains promote transcriptional repression in cervical cancer

Cervical cancer is the third female cancer most common worldwide. The carcinogenic process involves an alteration of the mechanisms associated with transcription. Several studies have reported an oncogenic role of the polycomb complex subunit, EZH2. However, the role of EZH2 in cervical cancer is un...

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Bibliographic Details
Main Authors: Eric Genaro Salmerón-Bárcenas, Ana Elvira Zacapala-Gómez, Julio Ortiz-Ortiz, Francisco Israel Torres-Rojas, Pedro Antonio Avila-Lopez
Format: Article
Language:English
Published: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund 2022-06-01
Series:EXCLI Journal : Experimental and Clinical Sciences
Subjects:
cervical cancer
ezh2-rich domains
silencers
chromatin domains
senescence
Online Access:https://www.excli.de/index.php/excli/article/view/5029

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