Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2

Abstract Hypomyopathic dermatomyositis (DM) presents with cutaneous lesions consistent with dermatomyositis but in the absence of clinically appreciable muscle weakness. The cutaneous manifestations are often refractory and more resistant to conventional therapy than concomitant muscle involvement....

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Main Authors: Miao Miao, Yuhui Li, Bo Huang, Jing He, Zhanguo Li
Format: Article
Language:English
Published: Adis, Springer Healthcare 2020-07-01
Series:Dermatology and Therapy
Subjects:
Online Access:https://doi.org/10.1007/s13555-020-00421-8
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author Miao Miao
Yuhui Li
Bo Huang
Jing He
Zhanguo Li
author_facet Miao Miao
Yuhui Li
Bo Huang
Jing He
Zhanguo Li
author_sort Miao Miao
collection DOAJ
description Abstract Hypomyopathic dermatomyositis (DM) presents with cutaneous lesions consistent with dermatomyositis but in the absence of clinically appreciable muscle weakness. The cutaneous manifestations are often refractory and more resistant to conventional therapy than concomitant muscle involvement. We present a 61-year-old hypomyopathic patient with DM who failed to respond to standard therapy but was successfully treated by low-dose interleukin-2 (IL-2) with no significant side effects. We conclude that low-dose IL-2 is a safe and effective treatment for hypomyopathic DM.
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spelling doaj.art-2eff63866d6a4ef99f9bf083b124547c2022-12-21T18:20:44ZengAdis, Springer HealthcareDermatology and Therapy2193-82102190-91722020-07-011051181118410.1007/s13555-020-00421-8Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2Miao Miao0Yuhui Li1Bo Huang2Jing He3Zhanguo Li4Department of Rheumatology and Immunology, Peking University People’s HospitalDepartment of Rheumatology and Immunology, Peking University People’s HospitalDepartment of Rheumatology and Immunology, Peking University People’s HospitalDepartment of Rheumatology and Immunology, Peking University People’s HospitalDepartment of Rheumatology and Immunology, Peking University People’s HospitalAbstract Hypomyopathic dermatomyositis (DM) presents with cutaneous lesions consistent with dermatomyositis but in the absence of clinically appreciable muscle weakness. The cutaneous manifestations are often refractory and more resistant to conventional therapy than concomitant muscle involvement. We present a 61-year-old hypomyopathic patient with DM who failed to respond to standard therapy but was successfully treated by low-dose interleukin-2 (IL-2) with no significant side effects. We conclude that low-dose IL-2 is a safe and effective treatment for hypomyopathic DM.https://doi.org/10.1007/s13555-020-00421-8Hypomyopathic dermatomyositisRefractory dermatitisLow-dose IL-2
spellingShingle Miao Miao
Yuhui Li
Bo Huang
Jing He
Zhanguo Li
Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
Dermatology and Therapy
Hypomyopathic dermatomyositis
Refractory dermatitis
Low-dose IL-2
title Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_full Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_fullStr Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_full_unstemmed Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_short Hypomyopathic Dermatomyositis with Refractory Dermatitis Treated by Low-dose IL-2
title_sort hypomyopathic dermatomyositis with refractory dermatitis treated by low dose il 2
topic Hypomyopathic dermatomyositis
Refractory dermatitis
Low-dose IL-2
url https://doi.org/10.1007/s13555-020-00421-8
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