Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy

The mobility of the human body depends on, among other things, muscle health, which can be affected by several situations, such as aging, increased oxidative stress, malnutrition, cancer, and the lack or excess of physical exercise, among others. Genetic, metabolic, hormonal, and nutritional factors...

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Main Authors: Nancy Vargas-Mendoza, Eduardo Madrigal-Santillán, Isela Álvarez-González, Eduardo Madrigal-Bujaidar, Liliana Anguiano-Robledo, José Leopoldo Aguilar-Faisal, Mauricio Morales-Martínez, Luis Delgado-Olivares, Elda Victoria Rodríguez-Negrete, Ángel Morales-González, José A. Morales-González
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Plants
Subjects:
Online Access:https://www.mdpi.com/2223-7747/11/19/2517
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author Nancy Vargas-Mendoza
Eduardo Madrigal-Santillán
Isela Álvarez-González
Eduardo Madrigal-Bujaidar
Liliana Anguiano-Robledo
José Leopoldo Aguilar-Faisal
Mauricio Morales-Martínez
Luis Delgado-Olivares
Elda Victoria Rodríguez-Negrete
Ángel Morales-González
José A. Morales-González
author_facet Nancy Vargas-Mendoza
Eduardo Madrigal-Santillán
Isela Álvarez-González
Eduardo Madrigal-Bujaidar
Liliana Anguiano-Robledo
José Leopoldo Aguilar-Faisal
Mauricio Morales-Martínez
Luis Delgado-Olivares
Elda Victoria Rodríguez-Negrete
Ángel Morales-González
José A. Morales-González
author_sort Nancy Vargas-Mendoza
collection DOAJ
description The mobility of the human body depends on, among other things, muscle health, which can be affected by several situations, such as aging, increased oxidative stress, malnutrition, cancer, and the lack or excess of physical exercise, among others. Genetic, metabolic, hormonal, and nutritional factors are intricately involved in maintaining the balance that allows proper muscle function and fiber recovery; therefore, the breakdown of the balance among these elements can trigger muscle atrophy. The study from the nutrigenomic perspective of nutritional factors has drawn wide attention recently; one of these is the use of certain compounds derived from foods and plants known as phytochemicals, to which various biological activities have been described and attributed in terms of benefiting health in many respects. This work addresses the effect that the phytochemicals curcumin from <i>Curcuma longa</i> Linn and sulforaphane from <i>Brassicaceae</i> species have shown to exert on muscle function, recovery, and the prevention of muscle atrophy, and describes the impact on muscle health in general. In the same manner, there are future perspectives in research on novel compounds as potential agents in the prevention or treatment of medical conditions that affect muscle health.
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spelling doaj.art-2f03576b4a4d4932b933365c52d206b82023-11-23T21:28:48ZengMDPI AGPlants2223-77472022-09-011119251710.3390/plants11192517Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle AtrophyNancy Vargas-Mendoza0Eduardo Madrigal-Santillán1Isela Álvarez-González2Eduardo Madrigal-Bujaidar3Liliana Anguiano-Robledo4José Leopoldo Aguilar-Faisal5Mauricio Morales-Martínez6Luis Delgado-Olivares7Elda Victoria Rodríguez-Negrete8Ángel Morales-González9José A. Morales-González10Laboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Unidad Profesional A. López Mateos, Av. Wilfrido Massieu. Col., Zacatenco, Mexico City 07738, MexicoEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Unidad Profesional A. López Mateos, Av. Wilfrido Massieu. Col., Zacatenco, Mexico City 07738, MexicoLaboratorio de Farmacología Molecular, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoLicenciatura en Nutrición, Universidad Intercontinental, Insurgentes Sur 4303, Santa Úrsula Xitla, Alcaldía Tlalpan, Mexico City 14420, MexicoCentro de Investigación Interdisciplinario, Área Académica de Nutrición, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Circuito Actopan-Tilcuauttla, s/n, Ex Hacienda la Concepción, San Agustín Tlaxiaca, Hidalgo 2160, MexicoServicio de Gastroenterología, Hospital de Especialidades Centro Medico Nacional Siglo 21, Mexico City 06720, MexicoEscuela Superior de Cómputo, Instituto Politécnico Nacional, Av. Juan de Dios Bátiz s/n Esquina Miguel Othón de Mendizabal, Unidad Profesional Adolfo López Mateos, Mexico City 07738, MexicoLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoThe mobility of the human body depends on, among other things, muscle health, which can be affected by several situations, such as aging, increased oxidative stress, malnutrition, cancer, and the lack or excess of physical exercise, among others. Genetic, metabolic, hormonal, and nutritional factors are intricately involved in maintaining the balance that allows proper muscle function and fiber recovery; therefore, the breakdown of the balance among these elements can trigger muscle atrophy. The study from the nutrigenomic perspective of nutritional factors has drawn wide attention recently; one of these is the use of certain compounds derived from foods and plants known as phytochemicals, to which various biological activities have been described and attributed in terms of benefiting health in many respects. This work addresses the effect that the phytochemicals curcumin from <i>Curcuma longa</i> Linn and sulforaphane from <i>Brassicaceae</i> species have shown to exert on muscle function, recovery, and the prevention of muscle atrophy, and describes the impact on muscle health in general. In the same manner, there are future perspectives in research on novel compounds as potential agents in the prevention or treatment of medical conditions that affect muscle health.https://www.mdpi.com/2223-7747/11/19/2517phytochemicalscurcuminsulforaphaneskeletal muscle
spellingShingle Nancy Vargas-Mendoza
Eduardo Madrigal-Santillán
Isela Álvarez-González
Eduardo Madrigal-Bujaidar
Liliana Anguiano-Robledo
José Leopoldo Aguilar-Faisal
Mauricio Morales-Martínez
Luis Delgado-Olivares
Elda Victoria Rodríguez-Negrete
Ángel Morales-González
José A. Morales-González
Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy
Plants
phytochemicals
curcumin
sulforaphane
skeletal muscle
title Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy
title_full Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy
title_fullStr Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy
title_full_unstemmed Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy
title_short Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy
title_sort phytochemicals in skeletal muscle health effects of curcumin from i curcuma longa linn i and sulforaphane from i brassicaceae i on muscle function recovery and therapy of muscle atrophy
topic phytochemicals
curcumin
sulforaphane
skeletal muscle
url https://www.mdpi.com/2223-7747/11/19/2517
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