Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy
The mobility of the human body depends on, among other things, muscle health, which can be affected by several situations, such as aging, increased oxidative stress, malnutrition, cancer, and the lack or excess of physical exercise, among others. Genetic, metabolic, hormonal, and nutritional factors...
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MDPI AG
2022-09-01
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author | Nancy Vargas-Mendoza Eduardo Madrigal-Santillán Isela Álvarez-González Eduardo Madrigal-Bujaidar Liliana Anguiano-Robledo José Leopoldo Aguilar-Faisal Mauricio Morales-Martínez Luis Delgado-Olivares Elda Victoria Rodríguez-Negrete Ángel Morales-González José A. Morales-González |
author_facet | Nancy Vargas-Mendoza Eduardo Madrigal-Santillán Isela Álvarez-González Eduardo Madrigal-Bujaidar Liliana Anguiano-Robledo José Leopoldo Aguilar-Faisal Mauricio Morales-Martínez Luis Delgado-Olivares Elda Victoria Rodríguez-Negrete Ángel Morales-González José A. Morales-González |
author_sort | Nancy Vargas-Mendoza |
collection | DOAJ |
description | The mobility of the human body depends on, among other things, muscle health, which can be affected by several situations, such as aging, increased oxidative stress, malnutrition, cancer, and the lack or excess of physical exercise, among others. Genetic, metabolic, hormonal, and nutritional factors are intricately involved in maintaining the balance that allows proper muscle function and fiber recovery; therefore, the breakdown of the balance among these elements can trigger muscle atrophy. The study from the nutrigenomic perspective of nutritional factors has drawn wide attention recently; one of these is the use of certain compounds derived from foods and plants known as phytochemicals, to which various biological activities have been described and attributed in terms of benefiting health in many respects. This work addresses the effect that the phytochemicals curcumin from <i>Curcuma longa</i> Linn and sulforaphane from <i>Brassicaceae</i> species have shown to exert on muscle function, recovery, and the prevention of muscle atrophy, and describes the impact on muscle health in general. In the same manner, there are future perspectives in research on novel compounds as potential agents in the prevention or treatment of medical conditions that affect muscle health. |
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spelling | doaj.art-2f03576b4a4d4932b933365c52d206b82023-11-23T21:28:48ZengMDPI AGPlants2223-77472022-09-011119251710.3390/plants11192517Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle AtrophyNancy Vargas-Mendoza0Eduardo Madrigal-Santillán1Isela Álvarez-González2Eduardo Madrigal-Bujaidar3Liliana Anguiano-Robledo4José Leopoldo Aguilar-Faisal5Mauricio Morales-Martínez6Luis Delgado-Olivares7Elda Victoria Rodríguez-Negrete8Ángel Morales-González9José A. Morales-González10Laboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Unidad Profesional A. López Mateos, Av. Wilfrido Massieu. Col., Zacatenco, Mexico City 07738, MexicoEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Unidad Profesional A. López Mateos, Av. Wilfrido Massieu. Col., Zacatenco, Mexico City 07738, MexicoLaboratorio de Farmacología Molecular, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoLicenciatura en Nutrición, Universidad Intercontinental, Insurgentes Sur 4303, Santa Úrsula Xitla, Alcaldía Tlalpan, Mexico City 14420, MexicoCentro de Investigación Interdisciplinario, Área Académica de Nutrición, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Circuito Actopan-Tilcuauttla, s/n, Ex Hacienda la Concepción, San Agustín Tlaxiaca, Hidalgo 2160, MexicoServicio de Gastroenterología, Hospital de Especialidades Centro Medico Nacional Siglo 21, Mexico City 06720, MexicoEscuela Superior de Cómputo, Instituto Politécnico Nacional, Av. Juan de Dios Bátiz s/n Esquina Miguel Othón de Mendizabal, Unidad Profesional Adolfo López Mateos, Mexico City 07738, MexicoLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Mexico City 11340, MexicoThe mobility of the human body depends on, among other things, muscle health, which can be affected by several situations, such as aging, increased oxidative stress, malnutrition, cancer, and the lack or excess of physical exercise, among others. Genetic, metabolic, hormonal, and nutritional factors are intricately involved in maintaining the balance that allows proper muscle function and fiber recovery; therefore, the breakdown of the balance among these elements can trigger muscle atrophy. The study from the nutrigenomic perspective of nutritional factors has drawn wide attention recently; one of these is the use of certain compounds derived from foods and plants known as phytochemicals, to which various biological activities have been described and attributed in terms of benefiting health in many respects. This work addresses the effect that the phytochemicals curcumin from <i>Curcuma longa</i> Linn and sulforaphane from <i>Brassicaceae</i> species have shown to exert on muscle function, recovery, and the prevention of muscle atrophy, and describes the impact on muscle health in general. In the same manner, there are future perspectives in research on novel compounds as potential agents in the prevention or treatment of medical conditions that affect muscle health.https://www.mdpi.com/2223-7747/11/19/2517phytochemicalscurcuminsulforaphaneskeletal muscle |
spellingShingle | Nancy Vargas-Mendoza Eduardo Madrigal-Santillán Isela Álvarez-González Eduardo Madrigal-Bujaidar Liliana Anguiano-Robledo José Leopoldo Aguilar-Faisal Mauricio Morales-Martínez Luis Delgado-Olivares Elda Victoria Rodríguez-Negrete Ángel Morales-González José A. Morales-González Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy Plants phytochemicals curcumin sulforaphane skeletal muscle |
title | Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy |
title_full | Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy |
title_fullStr | Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy |
title_full_unstemmed | Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy |
title_short | Phytochemicals in Skeletal Muscle Health: Effects of Curcumin (from <i>Curcuma longa Linn</i>) and Sulforaphane (from <i>Brassicaceae)</i> on Muscle Function, Recovery and Therapy of Muscle Atrophy |
title_sort | phytochemicals in skeletal muscle health effects of curcumin from i curcuma longa linn i and sulforaphane from i brassicaceae i on muscle function recovery and therapy of muscle atrophy |
topic | phytochemicals curcumin sulforaphane skeletal muscle |
url | https://www.mdpi.com/2223-7747/11/19/2517 |
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