Bufotalin Suppresses Proliferation and Metastasis of Triple-Negative Breast Cancer Cells by Promoting Apoptosis and Inhibiting the STAT3/EMT Axis

Bufotalin Suppresses Proliferation and Metastasis of Triple-Negative Breast Cancer Cells by Promoting Apoptosis and Inhibiting the STAT3/EMT Axis

Triple-negative breast cancer (TNBC) is a highly aggressive type of breast cancer and has a poor prognosis. As standardized TNBC treatment regimens cause drug resistance and tumor recurrence, the development of new TNBC treatment strategies is urgently required. Bufotalin is a bufadienolide isolated...

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Bibliographic Details
Main Authors: So Jin Park, Hye Jin Jung
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
triple-negative breast cancer
bufotalin
apoptosis
epithelial-mesenchymal transition
signal transducer and activator of transcription 3
Online Access:https://www.mdpi.com/1420-3049/28/19/6783

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