CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS
The goal of the study: to evaluate treatment efficiency of pulmonary tuberculosis patients resistant to rifampicin when treatment was prescribed based on the results of Xpert MBT/RIF. The social and clinical structure was retrospectively analyzed in 165 new pulmonary tuberculosis patients, treated i...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2017-10-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1042 |
| _version_ | 1826563097582632960 |
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| author | A. M. MАLIK |
| author_facet | A. M. MАLIK |
| author_sort | A. M. MАLIK |
| collection | DOAJ |
| description | The goal of the study: to evaluate treatment efficiency of pulmonary tuberculosis patients resistant to rifampicin when treatment was prescribed based on the results of Xpert MBT/RIF. The social and clinical structure was retrospectively analyzed in 165 new pulmonary tuberculosis patients, treated in the in-patient unit of Municipal Clinical Phthisiopulmonary Hospital (Kishineu Mun.). Patients were divided into 2 groups: the main group included 85 patients, in whom the result of Xpert MTB/RIF was positive and resistant to rifampicin, the control group included 80 patients in whom the result of Xpert MTB/RIF was positive and susceptible to rifampicin; certain parameters of the groups were compared. Only 65/80 (81.2%) patients of the control group had a complete treatment course, and 61/85 (71.8%) of the main group, the rest of the patients was lost to follow-up. Evaluation of the outcomes of the complete treatment course showed no confident difference between drug susceptible tuberculosis patients and those resistant to rifampicin, provided that treatment was prescribed with the consideration of Xpert MBT/RIF data. |
| first_indexed | 2024-03-12T03:29:39Z |
| format | Article |
| id | doaj.art-2f09b6517c6e4c7187747286258cb13c |
| institution | Directory Open Access Journal |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| last_indexed | 2025-03-14T09:58:33Z |
| publishDate | 2017-10-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj.art-2f09b6517c6e4c7187747286258cb13c2025-03-02T11:22:27ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062017-10-01959303310.21292/2075-1230-2017-95-9-30-331042CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTSA. M. MАLIK0State University of Medicine and Pharmaceutics "Nicolae Testemitanu"The goal of the study: to evaluate treatment efficiency of pulmonary tuberculosis patients resistant to rifampicin when treatment was prescribed based on the results of Xpert MBT/RIF. The social and clinical structure was retrospectively analyzed in 165 new pulmonary tuberculosis patients, treated in the in-patient unit of Municipal Clinical Phthisiopulmonary Hospital (Kishineu Mun.). Patients were divided into 2 groups: the main group included 85 patients, in whom the result of Xpert MTB/RIF was positive and resistant to rifampicin, the control group included 80 patients in whom the result of Xpert MTB/RIF was positive and susceptible to rifampicin; certain parameters of the groups were compared. Only 65/80 (81.2%) patients of the control group had a complete treatment course, and 61/85 (71.8%) of the main group, the rest of the patients was lost to follow-up. Evaluation of the outcomes of the complete treatment course showed no confident difference between drug susceptible tuberculosis patients and those resistant to rifampicin, provided that treatment was prescribed with the consideration of Xpert MBT/RIF data.https://www.tibl-journal.com/jour/article/view/1042xpert mtb/rifdrug susceptible tuberculosisdrug resistant tuberculosis |
| spellingShingle | A. M. MАLIK CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS Туберкулез и болезни лёгких xpert mtb/rif drug susceptible tuberculosis drug resistant tuberculosis |
| title | CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS |
| title_full | CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS |
| title_fullStr | CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS |
| title_full_unstemmed | CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS |
| title_short | CHARACTERISTICS AND EFFICIENCY OF TREATMENT IN TUBERCULOSIS PATIENTS DEPENDING ON THE ХPERT MTB/RIF RESULTS |
| title_sort | characteristics and efficiency of treatment in tuberculosis patients depending on the хpert mtb rif results |
| topic | xpert mtb/rif drug susceptible tuberculosis drug resistant tuberculosis |
| url | https://www.tibl-journal.com/jour/article/view/1042 |
| work_keys_str_mv | AT ammalik characteristicsandefficiencyoftreatmentintuberculosispatientsdependingonthehpertmtbrifresults |