Magnetite-silica core-shell nanostructures: Application for photodynamic therapy

Magnetite nanoparticles have been synthesized with chemical co-precipitation. The surface of magnetite nanoparticles was coated with an inorganic silica layer by hydrolyzing and condensing tetraethyl orthosilicate. An XRD investigation supports the cubic inverse spinel structure of Fe3O4 nanoparticl...

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Main Authors: Kaur Kamaldeep, Singh Arashdeep, Jindal Shivani
Format: Article
Language:English
Published: EDP Sciences 2024-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/39/e3sconf_iconn2024_02006.pdf
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author Kaur Kamaldeep
Singh Arashdeep
Jindal Shivani
author_facet Kaur Kamaldeep
Singh Arashdeep
Jindal Shivani
author_sort Kaur Kamaldeep
collection DOAJ
description Magnetite nanoparticles have been synthesized with chemical co-precipitation. The surface of magnetite nanoparticles was coated with an inorganic silica layer by hydrolyzing and condensing tetraethyl orthosilicate. An XRD investigation supports the cubic inverse spinel structure of Fe3O4 nanoparticles. The average crystallite size of the magnetite nanoparticles produced by the peak broadening was 13 nm. The UV-visible spectrum of methylene blue-loaded magnetite-silica nanoparticles shows a strong hump at 657 nm. According to TEM examination, the nanoparticles are polydisperse and almost spherical in form.The average size of the nanoparticles is 14.39 nm plus 1.66 nm, and they have a polydispersity index of 0.12%.The size and shape of the core-shell particles are not uniform, according to a SEM examination. There is no distinguishing morphology in any sample.The magnetic results depicts the superparamagnetic behaviour of nanoparticlesmakes them suitable for photodynamic therapy.
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spelling doaj.art-2f0cb97ebe39454984bbee2d3e197a6a2024-04-12T07:41:04ZengEDP SciencesE3S Web of Conferences2267-12422024-01-015090200610.1051/e3sconf/202450902006e3sconf_iconn2024_02006Magnetite-silica core-shell nanostructures: Application for photodynamic therapyKaur Kamaldeep0Singh Arashdeep1Jindal Shivani2University Institute of Sciences, Chandigarh UniversityElectrical Department,Chandigarh UniversityDepartment of Applied Science, Thapar Polytechnic CollegeMagnetite nanoparticles have been synthesized with chemical co-precipitation. The surface of magnetite nanoparticles was coated with an inorganic silica layer by hydrolyzing and condensing tetraethyl orthosilicate. An XRD investigation supports the cubic inverse spinel structure of Fe3O4 nanoparticles. The average crystallite size of the magnetite nanoparticles produced by the peak broadening was 13 nm. The UV-visible spectrum of methylene blue-loaded magnetite-silica nanoparticles shows a strong hump at 657 nm. According to TEM examination, the nanoparticles are polydisperse and almost spherical in form.The average size of the nanoparticles is 14.39 nm plus 1.66 nm, and they have a polydispersity index of 0.12%.The size and shape of the core-shell particles are not uniform, according to a SEM examination. There is no distinguishing morphology in any sample.The magnetic results depicts the superparamagnetic behaviour of nanoparticlesmakes them suitable for photodynamic therapy.https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/39/e3sconf_iconn2024_02006.pdf
spellingShingle Kaur Kamaldeep
Singh Arashdeep
Jindal Shivani
Magnetite-silica core-shell nanostructures: Application for photodynamic therapy
E3S Web of Conferences
title Magnetite-silica core-shell nanostructures: Application for photodynamic therapy
title_full Magnetite-silica core-shell nanostructures: Application for photodynamic therapy
title_fullStr Magnetite-silica core-shell nanostructures: Application for photodynamic therapy
title_full_unstemmed Magnetite-silica core-shell nanostructures: Application for photodynamic therapy
title_short Magnetite-silica core-shell nanostructures: Application for photodynamic therapy
title_sort magnetite silica core shell nanostructures application for photodynamic therapy
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2024/39/e3sconf_iconn2024_02006.pdf
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AT singharashdeep magnetitesilicacoreshellnanostructuresapplicationforphotodynamictherapy
AT jindalshivani magnetitesilicacoreshellnanostructuresapplicationforphotodynamictherapy