Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findings

The aim of this case report is to present real-time CEUS-guided biopsy for diagnosing rare benign splenic pathologies after inconclusive findings on cross-sectional imaging. We present the case of a 50-year-old male patient who received a contrast-enhanced computed tomography scan of the thorax duri...

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Main Authors: Lerchbaumer Markus Herbert, Althoff Christian E., Fischer Thomas
Format: Article
Language:English
Published: Sciendo 2021-08-01
Series:Journal of Ultrasonography
Subjects:
Online Access:https://doi.org/10.15557/jou.2021.0039
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author Lerchbaumer Markus Herbert
Althoff Christian E.
Fischer Thomas
author_facet Lerchbaumer Markus Herbert
Althoff Christian E.
Fischer Thomas
author_sort Lerchbaumer Markus Herbert
collection DOAJ
description The aim of this case report is to present real-time CEUS-guided biopsy for diagnosing rare benign splenic pathologies after inconclusive findings on cross-sectional imaging. We present the case of a 50-year-old male patient who received a contrast-enhanced computed tomography scan of the thorax during the evaluation for lung transplant due to lung fibrosis, with incidental finding of disseminated hypodense splenic lesions. During follow-up imaging, the patient did not tolerate a complete MRI examination, and two acquired pulse sequences did not confirm the final diagnosis. While CT-guided biopsy revealed no results, CEUS-guided target biopsy with repeated contrast injections showed a benign littoral cell angioma of the spleen. The use of real-time CEUS-guided target biopsy during lesion washout may be a useful tool to improve the accuracy of biopsy and accelerate the diagnosis in patients with parenchymal lesions after inconclusive cross-sectional imaging findings which may pose a challenge for CT-guided biopsy.
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spelling doaj.art-2f0de683b490408eac2401df734425412022-12-22T01:33:49ZengSciendoJournal of Ultrasonography2451-070X2021-08-01218624424710.15557/jou.2021.0039Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findingsLerchbaumer Markus Herbert0Althoff Christian E.1Fischer Thomas2Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humbold-Universität zu Berlin, and Berlin Institute of Health, Department of Radiology, Berlin, GermanyCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humbold-Universität zu Berlin, and Berlin Institute of Health, Department of Radiology, Berlin, GermanyCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humbold-Universität zu Berlin, and Berlin Institute of Health, Department of Radiology, Berlin, GermanyThe aim of this case report is to present real-time CEUS-guided biopsy for diagnosing rare benign splenic pathologies after inconclusive findings on cross-sectional imaging. We present the case of a 50-year-old male patient who received a contrast-enhanced computed tomography scan of the thorax during the evaluation for lung transplant due to lung fibrosis, with incidental finding of disseminated hypodense splenic lesions. During follow-up imaging, the patient did not tolerate a complete MRI examination, and two acquired pulse sequences did not confirm the final diagnosis. While CT-guided biopsy revealed no results, CEUS-guided target biopsy with repeated contrast injections showed a benign littoral cell angioma of the spleen. The use of real-time CEUS-guided target biopsy during lesion washout may be a useful tool to improve the accuracy of biopsy and accelerate the diagnosis in patients with parenchymal lesions after inconclusive cross-sectional imaging findings which may pose a challenge for CT-guided biopsy.https://doi.org/10.15557/jou.2021.0039ceuscontrast-enhanced ultrasoundceus-guided target biopsylittoral cell angiomaspleen
spellingShingle Lerchbaumer Markus Herbert
Althoff Christian E.
Fischer Thomas
Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findings
Journal of Ultrasonography
ceus
contrast-enhanced ultrasound
ceus-guided target biopsy
littoral cell angioma
spleen
title Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findings
title_full Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findings
title_fullStr Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findings
title_full_unstemmed Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findings
title_short Real-time CEUS-guided biopsy revealing a littoral cell angioma of the spleen after inconclusive CT and MRI findings
title_sort real time ceus guided biopsy revealing a littoral cell angioma of the spleen after inconclusive ct and mri findings
topic ceus
contrast-enhanced ultrasound
ceus-guided target biopsy
littoral cell angioma
spleen
url https://doi.org/10.15557/jou.2021.0039
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