Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia.
<h4>Background</h4>Asymptomatic Plasmodium infection (API) that occurs during pregnancy increases the risk of stillbirths, abortion, premature delivery, and low birth weight. API also hinders the control and prevention of malaria as infected hosts serve as silent reservoirs for transmiss...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0248074 |
| _version_ | 1818729837543555072 |
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| author | Bereket Wake Subussa Teferi Eshetu Teshome Degefa Musa Mohammed Ali |
| author_facet | Bereket Wake Subussa Teferi Eshetu Teshome Degefa Musa Mohammed Ali |
| author_sort | Bereket Wake Subussa |
| collection | DOAJ |
| description | <h4>Background</h4>Asymptomatic Plasmodium infection (API) that occurs during pregnancy increases the risk of stillbirths, abortion, premature delivery, and low birth weight. API also hinders the control and prevention of malaria as infected hosts serve as silent reservoirs for transmission of Plasmodium species in the community.<h4>Objective</h4>The aim of this study was to determine the prevalence of API and associated factors among pregnant women. This community-based cross-sectional study was conducted at Merti district, Oromia, Ethiopia among 364 pregnant women from March to September 2018.<h4>Methods</h4>Sociodemographic and obstetrics features were collected using a structured questionnaire. About 2ml of blood was collected from participants to detect Plasmodium species, gametocyte carriage rate, parasite density, and anemia.<h4>Results</h4>The prevalence of API among pregnant women was 3.6%. The proportion of Plasmodium falciparum and Plasmodium vivax was 6(46.2%) and 7(53.8%) respectively. Out of 13 Plasmodium species identified, Gametocyte carriage rate was 4(30.7%). The geometric mean density of the asexual stage of the parasites was 994.7(interquartile [IQR], 320 to 2200) parasites/ul. The geometric mean gametocyte density was 303.3 (interquartile range [IQR], 160 to 600). The proportion of anemia among Plasmodium-infected participants was 12(92.3%). Previous infection by Plasmodium species (AOR = 5.42; 95% CI: 1.19-29.03, p = 0.047), lack of insecticide-treated bed net use (AOR = 6.52; 95% CI: 1.17-36.44, p = 0.032), and living close to stagnant water (AOR = 4.18; 95% CI (1.12-17.36, p = 0.049) were significantly associated with API. Anemia was significantly higher among Plasmodium-infected than non-infected pregnant women (x2 = 27.62, p <0.001).<h4>Conclusion</h4>In the current study, a relatively high prevalence of API was detected among pregnant women. Identifying API in the community is important to prevent the unwanted outcomes of Plasmodium infection and its transmission. |
| first_indexed | 2024-12-17T22:52:14Z |
| format | Article |
| id | doaj.art-2f116fffcf29419eb4f4125e5a47bc67 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-17T22:52:14Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-2f116fffcf29419eb4f4125e5a47bc672022-12-21T21:29:38ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01163e024807410.1371/journal.pone.0248074Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia.Bereket Wake SubussaTeferi EshetuTeshome DegefaMusa Mohammed Ali<h4>Background</h4>Asymptomatic Plasmodium infection (API) that occurs during pregnancy increases the risk of stillbirths, abortion, premature delivery, and low birth weight. API also hinders the control and prevention of malaria as infected hosts serve as silent reservoirs for transmission of Plasmodium species in the community.<h4>Objective</h4>The aim of this study was to determine the prevalence of API and associated factors among pregnant women. This community-based cross-sectional study was conducted at Merti district, Oromia, Ethiopia among 364 pregnant women from March to September 2018.<h4>Methods</h4>Sociodemographic and obstetrics features were collected using a structured questionnaire. About 2ml of blood was collected from participants to detect Plasmodium species, gametocyte carriage rate, parasite density, and anemia.<h4>Results</h4>The prevalence of API among pregnant women was 3.6%. The proportion of Plasmodium falciparum and Plasmodium vivax was 6(46.2%) and 7(53.8%) respectively. Out of 13 Plasmodium species identified, Gametocyte carriage rate was 4(30.7%). The geometric mean density of the asexual stage of the parasites was 994.7(interquartile [IQR], 320 to 2200) parasites/ul. The geometric mean gametocyte density was 303.3 (interquartile range [IQR], 160 to 600). The proportion of anemia among Plasmodium-infected participants was 12(92.3%). Previous infection by Plasmodium species (AOR = 5.42; 95% CI: 1.19-29.03, p = 0.047), lack of insecticide-treated bed net use (AOR = 6.52; 95% CI: 1.17-36.44, p = 0.032), and living close to stagnant water (AOR = 4.18; 95% CI (1.12-17.36, p = 0.049) were significantly associated with API. Anemia was significantly higher among Plasmodium-infected than non-infected pregnant women (x2 = 27.62, p <0.001).<h4>Conclusion</h4>In the current study, a relatively high prevalence of API was detected among pregnant women. Identifying API in the community is important to prevent the unwanted outcomes of Plasmodium infection and its transmission.https://doi.org/10.1371/journal.pone.0248074 |
| spellingShingle | Bereket Wake Subussa Teferi Eshetu Teshome Degefa Musa Mohammed Ali Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia. PLoS ONE |
| title | Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia. |
| title_full | Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia. |
| title_fullStr | Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia. |
| title_full_unstemmed | Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia. |
| title_short | Asymptomatic Plasmodium infection and associated factors among pregnant women in the Merti district, Oromia, Ethiopia. |
| title_sort | asymptomatic plasmodium infection and associated factors among pregnant women in the merti district oromia ethiopia |
| url | https://doi.org/10.1371/journal.pone.0248074 |
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