Role of fine needle aspiration cytology in the diagnosis of thyroid lesions
<p><strong>Background: </strong>Fine needle aspiration cytology is regarded as a gold standard investigation in diagnosis of thyroid swellings. This study was carried out to evaluate the role of fine needle aspiration cytology as a diagnostic tool in investigation of thyroid swelli...
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| Format: | Article |
| Language: | English |
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Association of Clinical Pathologists of Nepal
2012-03-01
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| Series: | Journal of Pathology of Nepal |
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| Online Access: | http://www.nepjol.info/index.php/JPN/article/view/6018 |
| _version_ | 1819015319367188480 |
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| author | S Bhatta R Makaju A Mohammad |
| author_facet | S Bhatta R Makaju A Mohammad |
| author_sort | S Bhatta |
| collection | DOAJ |
| description | <p><strong>Background: </strong>Fine needle aspiration cytology is regarded as a gold standard investigation in diagnosis of thyroid swellings. This study was carried out to evaluate the role of fine needle aspiration cytology as a diagnostic tool in investigation of thyroid swelling and to correlate the cytological findings with histopathology.</p> <p><strong>Materials and Methods: </strong>A total of 90 patients with thyroid lesions submitted for fine needle aspiration cytology at Dhulikhel hospital Kathmandu Univeristy hospital over a four year period (May 2004 to May 2008) were studied.</p> <p><strong>Results: </strong>Majority of cases were non neoplastic (77 cases, 85.55 %), whereas 13 cases (14.45 %) were neoplastic. Tissue examination was available for subsequent histocytological correlation in 20 cases (22.22 %). The accuracy of cytodiagnosis was 90 % with a sensitivity of 85.7 %, specificity of 92.3 %, false negative rate of 14.28% and false positive rate of 7.69%.</p> <p><strong>Conclusion: </strong>Fine needle aspiration cytology of thyroid lesions provides a reliable diagnosis and is an excellent first line method for investigating the nature of lesion.<strong> </strong></p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v2i3.6018">http://dx.doi.org/10.3126/jpn.v2i3.6018</a></p> <p><em>JPN </em>2012; 2(3): 186-188<strong></strong></p> |
| first_indexed | 2024-12-21T02:29:51Z |
| format | Article |
| id | doaj.art-2f120d3633d2495f9e532dec92b34474 |
| institution | Directory Open Access Journal |
| issn | 2091-0797 2091-0908 |
| language | English |
| last_indexed | 2024-12-21T02:29:51Z |
| publishDate | 2012-03-01 |
| publisher | Association of Clinical Pathologists of Nepal |
| record_format | Article |
| series | Journal of Pathology of Nepal |
| spelling | doaj.art-2f120d3633d2495f9e532dec92b344742022-12-21T19:18:57ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082012-03-012318618810.3126/jpn.v2i3.60184878Role of fine needle aspiration cytology in the diagnosis of thyroid lesionsS Bhatta0R Makaju1A Mohammad2Department of Pathology, KIST Medical College, LalitpurDepartment of Pathology, Kathmandu University School of Medical Sciences, DhulikhelDepartment of Pathology, Kathmandu University School of Medical Sciences, Dhulikhel<p><strong>Background: </strong>Fine needle aspiration cytology is regarded as a gold standard investigation in diagnosis of thyroid swellings. This study was carried out to evaluate the role of fine needle aspiration cytology as a diagnostic tool in investigation of thyroid swelling and to correlate the cytological findings with histopathology.</p> <p><strong>Materials and Methods: </strong>A total of 90 patients with thyroid lesions submitted for fine needle aspiration cytology at Dhulikhel hospital Kathmandu Univeristy hospital over a four year period (May 2004 to May 2008) were studied.</p> <p><strong>Results: </strong>Majority of cases were non neoplastic (77 cases, 85.55 %), whereas 13 cases (14.45 %) were neoplastic. Tissue examination was available for subsequent histocytological correlation in 20 cases (22.22 %). The accuracy of cytodiagnosis was 90 % with a sensitivity of 85.7 %, specificity of 92.3 %, false negative rate of 14.28% and false positive rate of 7.69%.</p> <p><strong>Conclusion: </strong>Fine needle aspiration cytology of thyroid lesions provides a reliable diagnosis and is an excellent first line method for investigating the nature of lesion.<strong> </strong></p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v2i3.6018">http://dx.doi.org/10.3126/jpn.v2i3.6018</a></p> <p><em>JPN </em>2012; 2(3): 186-188<strong></strong></p>http://www.nepjol.info/index.php/JPN/article/view/6018Fine needle aspirationThyroidNeoplasmHistopathology |
| spellingShingle | S Bhatta R Makaju A Mohammad Role of fine needle aspiration cytology in the diagnosis of thyroid lesions Journal of Pathology of Nepal Fine needle aspiration Thyroid Neoplasm Histopathology |
| title | Role of fine needle aspiration cytology in the diagnosis of thyroid lesions |
| title_full | Role of fine needle aspiration cytology in the diagnosis of thyroid lesions |
| title_fullStr | Role of fine needle aspiration cytology in the diagnosis of thyroid lesions |
| title_full_unstemmed | Role of fine needle aspiration cytology in the diagnosis of thyroid lesions |
| title_short | Role of fine needle aspiration cytology in the diagnosis of thyroid lesions |
| title_sort | role of fine needle aspiration cytology in the diagnosis of thyroid lesions |
| topic | Fine needle aspiration Thyroid Neoplasm Histopathology |
| url | http://www.nepjol.info/index.php/JPN/article/view/6018 |
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