Protective effects of menthol against sepsis-induced hepatic injury: Role of mediators of hepatic inflammation, apoptosis, and regeneration

Protective effects of menthol against sepsis-induced hepatic injury: Role of mediators of hepatic inflammation, apoptosis, and regeneration

Liver dysfunction in sepsis is a major complication that amplifies multiple organ failure and increases the risk of death. Inflammation and oxidative stress are the main mediators in the pathophysiology of sepsis. Therefore, we investigated the role of menthol, a natural antioxidant, against sepsis-...

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Bibliographic Details
Main Authors: Asmaa I. Matouk, Mahmoud El-Daly, Heba A. Habib, Shaymaa Senousy, Sara Mohamed Naguib Abdel Hafez, AlShaimaa W. Kasem, Waleed Hassan Almalki, Abdulaziz Alzahrani, Ahmed Alshehri, Al-Shaimaa F. Ahmed
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
clp
hepatoprotection
tNF-alpha
PCNA
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.952337/full

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