Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor
In this study, we have first developed a rapid and sensitive strip immunosensor based on two heterogeneously-sized gold nanoparticles (Au NPs) probes for the detection of trace lead ions in drinking water. The sensitivity was 4-fold higher than that of the conventional LFA under the optimized condit...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-03-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/13/4/4214 |
| _version_ | 1798042174165614592 |
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| author | Chuanlai Xu Libing Wang Liqiang Liu Changlong Hao Changrui Xing Hua Kuang |
| author_facet | Chuanlai Xu Libing Wang Liqiang Liu Changlong Hao Changrui Xing Hua Kuang |
| author_sort | Chuanlai Xu |
| collection | DOAJ |
| description | In this study, we have first developed a rapid and sensitive strip immunosensor based on two heterogeneously-sized gold nanoparticles (Au NPs) probes for the detection of trace lead ions in drinking water. The sensitivity was 4-fold higher than that of the conventional LFA under the optimized conditions. The visual limit of detection (LOD) of the amplified method for qualitative detection lead ions was 2 ng/mL and the LOD for semi-quantitative detection could go down to 0.19 ng/mL using a scanning reader. The method suffered from no interference from other metal ions and could be used to detect trace lead ions in drinking water without sample enrichment. The recovery of the test samples ranged from 96% to 103%. As the detection method could be accomplished within 15 min, this method could be used as a potential tool for preliminary monitoring of lead contamination in drinking water. |
| first_indexed | 2024-04-11T22:31:49Z |
| format | Article |
| id | doaj.art-2f15991bac1741c5b94f39447dece795 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T22:31:49Z |
| publishDate | 2013-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-2f15991bac1741c5b94f39447dece7952022-12-22T03:59:22ZengMDPI AGSensors1424-82202013-03-011344214422410.3390/s130404214Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip ImmunosensorChuanlai XuLibing WangLiqiang LiuChanglong HaoChangrui XingHua KuangIn this study, we have first developed a rapid and sensitive strip immunosensor based on two heterogeneously-sized gold nanoparticles (Au NPs) probes for the detection of trace lead ions in drinking water. The sensitivity was 4-fold higher than that of the conventional LFA under the optimized conditions. The visual limit of detection (LOD) of the amplified method for qualitative detection lead ions was 2 ng/mL and the LOD for semi-quantitative detection could go down to 0.19 ng/mL using a scanning reader. The method suffered from no interference from other metal ions and could be used to detect trace lead ions in drinking water without sample enrichment. The recovery of the test samples ranged from 96% to 103%. As the detection method could be accomplished within 15 min, this method could be used as a potential tool for preliminary monitoring of lead contamination in drinking water.http://www.mdpi.com/1424-8220/13/4/4214amplified competitive lateral flow assaylead ionsimmunosensorgold nanoparticles |
| spellingShingle | Chuanlai Xu Libing Wang Liqiang Liu Changlong Hao Changrui Xing Hua Kuang Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor Sensors amplified competitive lateral flow assay lead ions immunosensor gold nanoparticles |
| title | Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor |
| title_full | Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor |
| title_fullStr | Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor |
| title_full_unstemmed | Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor |
| title_short | Rapid and Highly Sensitive Detection of Lead Ions in Drinking Water Based on a Strip Immunosensor |
| title_sort | rapid and highly sensitive detection of lead ions in drinking water based on a strip immunosensor |
| topic | amplified competitive lateral flow assay lead ions immunosensor gold nanoparticles |
| url | http://www.mdpi.com/1424-8220/13/4/4214 |
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