Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube Defects
Prenatal screening with α-fetoprotein (AFP) and ultrasonography have allowed the prenatal diagnosis of neural tube defects (NTDs) in current obstetric care, and open spina bifida has been considered a potential candidate for in utero treatment in modern pediatric surgery. This article provides an ov...
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| Format: | Article |
| Language: | English |
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Elsevier
2008-09-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455908601254 |
| _version_ | 1818243137101889536 |
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| author | Chih-Ping Chen |
| author_facet | Chih-Ping Chen |
| author_sort | Chih-Ping Chen |
| collection | DOAJ |
| description | Prenatal screening with α-fetoprotein (AFP) and ultrasonography have allowed the prenatal diagnosis of neural tube defects (NTDs) in current obstetric care, and open spina bifida has been considered a potential candidate for in utero treatment in modern pediatric surgery. This article provides an overview of maternal serum AFP screening, amniotic fluid AFP assays, amniotic fluid acetylcholinesterase immunoassays and level II ultrasound for NTDs, prenatal repair of fetal myelomeningocele, recurrence risk of NTDs, and differential diagnosis of NTDs on prenatal ultrasound. |
| first_indexed | 2024-12-12T13:56:20Z |
| format | Article |
| id | doaj.art-2f1600bd0cc241dba44a0118163b585a |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-12T13:56:20Z |
| publishDate | 2008-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-2f1600bd0cc241dba44a0118163b585a2022-12-22T00:22:28ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592008-09-0147328329010.1016/S1028-4559(08)60125-4Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube DefectsChih-Ping Chen0Department of Obstetrics and Gynecology, TaipeiPrenatal screening with α-fetoprotein (AFP) and ultrasonography have allowed the prenatal diagnosis of neural tube defects (NTDs) in current obstetric care, and open spina bifida has been considered a potential candidate for in utero treatment in modern pediatric surgery. This article provides an overview of maternal serum AFP screening, amniotic fluid AFP assays, amniotic fluid acetylcholinesterase immunoassays and level II ultrasound for NTDs, prenatal repair of fetal myelomeningocele, recurrence risk of NTDs, and differential diagnosis of NTDs on prenatal ultrasound.http://www.sciencedirect.com/science/article/pii/S1028455908601254acetylcholinesteraseα-fetoproteindifferential diagnosisneural tube defectsprenatal diagnosisrecurrence riskultrasound |
| spellingShingle | Chih-Ping Chen Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube Defects Taiwanese Journal of Obstetrics & Gynecology acetylcholinesterase α-fetoprotein differential diagnosis neural tube defects prenatal diagnosis recurrence risk ultrasound |
| title | Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube Defects |
| title_full | Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube Defects |
| title_fullStr | Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube Defects |
| title_full_unstemmed | Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube Defects |
| title_short | Prenatal Diagnosis, Fetal Surgery, Recurrence Risk and Differential Diagnosis of Neural Tube Defects |
| title_sort | prenatal diagnosis fetal surgery recurrence risk and differential diagnosis of neural tube defects |
| topic | acetylcholinesterase α-fetoprotein differential diagnosis neural tube defects prenatal diagnosis recurrence risk ultrasound |
| url | http://www.sciencedirect.com/science/article/pii/S1028455908601254 |
| work_keys_str_mv | AT chihpingchen prenataldiagnosisfetalsurgeryrecurrenceriskanddifferentialdiagnosisofneuraltubedefects |