Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications
Graphene is a two-dimensional sp<sup>2</sup> hybridized carbon material that has attracted tremendous attention for its stimuli-responsive applications, owing to its high surface area and excellent electrical, optical, thermal, and mechanical properties. The physicochemical properties of...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/9/2797 |
| _version_ | 1797534783818956800 |
|---|---|
| author | Tejal V. Patil Dinesh K. Patel Sayan Deb Dutta Keya Ganguly Ki-Taek Lim |
| author_facet | Tejal V. Patil Dinesh K. Patel Sayan Deb Dutta Keya Ganguly Ki-Taek Lim |
| author_sort | Tejal V. Patil |
| collection | DOAJ |
| description | Graphene is a two-dimensional sp<sup>2</sup> hybridized carbon material that has attracted tremendous attention for its stimuli-responsive applications, owing to its high surface area and excellent electrical, optical, thermal, and mechanical properties. The physicochemical properties of graphene can be tuned by surface functionalization. The biomedical field pays special attention to stimuli-responsive materials due to their responsive abilities under different conditions. Stimuli-responsive materials exhibit great potential in changing their behavior upon exposure to external or internal factors, such as pH, light, electric field, magnetic field, and temperature. Graphene-based materials, particularly graphene oxide (GO), have been widely used in stimuli-responsive applications due to their superior biocompatibility compared to other forms of graphene. GO has been commonly utilized in tissue engineering, bioimaging, biosensing, cancer therapy, and drug delivery. GO-based stimuli-responsive platforms for wound healing applications have not yet been fully explored. This review describes the effects of different stimuli-responsive factors, such as pH, light, temperature, and magnetic and electric fields on GO-based materials and their applications. The wound healing applications of GO-based materials is extensively discussed with cancer therapy and drug delivery. |
| first_indexed | 2024-03-10T11:34:26Z |
| format | Article |
| id | doaj.art-2f16325037bc456d97ff754e2aecf2dd |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T11:34:26Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-2f16325037bc456d97ff754e2aecf2dd2023-11-21T18:56:30ZengMDPI AGMolecules1420-30492021-05-01269279710.3390/molecules26092797Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical ApplicationsTejal V. Patil0Dinesh K. Patel1Sayan Deb Dutta2Keya Ganguly3Ki-Taek Lim4Department of Biosystems Engineering, Institute of Forest Science, Kangwon National University, Chuncheon 24341, KoreaDepartment of Biosystems Engineering, Institute of Forest Science, Kangwon National University, Chuncheon 24341, KoreaDepartment of Biosystems Engineering, Institute of Forest Science, Kangwon National University, Chuncheon 24341, KoreaDepartment of Biosystems Engineering, Institute of Forest Science, Kangwon National University, Chuncheon 24341, KoreaDepartment of Biosystems Engineering, Institute of Forest Science, Kangwon National University, Chuncheon 24341, KoreaGraphene is a two-dimensional sp<sup>2</sup> hybridized carbon material that has attracted tremendous attention for its stimuli-responsive applications, owing to its high surface area and excellent electrical, optical, thermal, and mechanical properties. The physicochemical properties of graphene can be tuned by surface functionalization. The biomedical field pays special attention to stimuli-responsive materials due to their responsive abilities under different conditions. Stimuli-responsive materials exhibit great potential in changing their behavior upon exposure to external or internal factors, such as pH, light, electric field, magnetic field, and temperature. Graphene-based materials, particularly graphene oxide (GO), have been widely used in stimuli-responsive applications due to their superior biocompatibility compared to other forms of graphene. GO has been commonly utilized in tissue engineering, bioimaging, biosensing, cancer therapy, and drug delivery. GO-based stimuli-responsive platforms for wound healing applications have not yet been fully explored. This review describes the effects of different stimuli-responsive factors, such as pH, light, temperature, and magnetic and electric fields on GO-based materials and their applications. The wound healing applications of GO-based materials is extensively discussed with cancer therapy and drug delivery.https://www.mdpi.com/1420-3049/26/9/2797graphene oxidestimuli-responsivepHwound healingcancer therapydrug delivery |
| spellingShingle | Tejal V. Patil Dinesh K. Patel Sayan Deb Dutta Keya Ganguly Ki-Taek Lim Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications Molecules graphene oxide stimuli-responsive pH wound healing cancer therapy drug delivery |
| title | Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications |
| title_full | Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications |
| title_fullStr | Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications |
| title_full_unstemmed | Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications |
| title_short | Graphene Oxide-Based Stimuli-Responsive Platforms for Biomedical Applications |
| title_sort | graphene oxide based stimuli responsive platforms for biomedical applications |
| topic | graphene oxide stimuli-responsive pH wound healing cancer therapy drug delivery |
| url | https://www.mdpi.com/1420-3049/26/9/2797 |
| work_keys_str_mv | AT tejalvpatil grapheneoxidebasedstimuliresponsiveplatformsforbiomedicalapplications AT dineshkpatel grapheneoxidebasedstimuliresponsiveplatformsforbiomedicalapplications AT sayandebdutta grapheneoxidebasedstimuliresponsiveplatformsforbiomedicalapplications AT keyaganguly grapheneoxidebasedstimuliresponsiveplatformsforbiomedicalapplications AT kitaeklim grapheneoxidebasedstimuliresponsiveplatformsforbiomedicalapplications |