Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products
Natural toxins include a wide range of toxic metabolites also occurring in food and products, thus representing a risk for consumer health. In the last few decades, several robust and sensitive analytical methods able to determine their occurrence in food have been developed. Liquid chromatography m...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Toxins |
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| Online Access: | https://www.mdpi.com/2072-6651/14/5/328 |
| _version_ | 1827666165827108864 |
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| author | Annalisa De Girolamo Vincenzo Lippolis Michelangelo Pascale |
| author_facet | Annalisa De Girolamo Vincenzo Lippolis Michelangelo Pascale |
| author_sort | Annalisa De Girolamo |
| collection | DOAJ |
| description | Natural toxins include a wide range of toxic metabolites also occurring in food and products, thus representing a risk for consumer health. In the last few decades, several robust and sensitive analytical methods able to determine their occurrence in food have been developed. Liquid chromatography mass spectrometry is the most powerful tool for the simultaneous detection of these toxins due to its advantages in terms of sensitivity and selectivity. A comprehensive review on the most relevant papers on methods based on liquid chromatography mass spectrometry for the analysis of mycotoxins, alkaloids, marine toxins, glycoalkaloids, cyanogenic glycosides and furocoumarins in food is reported herein. Specifically, a literature search from 2011 to 2021 was carried out, selecting a total of 96 papers. Different approaches to sample preparation, chromatographic separation and detection mode are discussed. Particular attention is given to the analytical performance characteristics obtained in the validation process and the relevant application to real samples. |
| first_indexed | 2024-03-10T01:41:07Z |
| format | Article |
| id | doaj.art-2f177b20067944d39cc49a790a69e763 |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-03-10T01:41:07Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-2f177b20067944d39cc49a790a69e7632023-11-23T13:22:59ZengMDPI AGToxins2072-66512022-05-0114532810.3390/toxins14050328Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food ProductsAnnalisa De Girolamo0Vincenzo Lippolis1Michelangelo Pascale2Institute of Sciences of Food Production (ISPA), National Research Council of Italy (CNR), 70126 Bari, ItalyInstitute of Sciences of Food Production (ISPA), National Research Council of Italy (CNR), 70126 Bari, ItalyInstitute of Food Sciences (ISA), National Research Council (CNR), 83100 Roma, ItalyNatural toxins include a wide range of toxic metabolites also occurring in food and products, thus representing a risk for consumer health. In the last few decades, several robust and sensitive analytical methods able to determine their occurrence in food have been developed. Liquid chromatography mass spectrometry is the most powerful tool for the simultaneous detection of these toxins due to its advantages in terms of sensitivity and selectivity. A comprehensive review on the most relevant papers on methods based on liquid chromatography mass spectrometry for the analysis of mycotoxins, alkaloids, marine toxins, glycoalkaloids, cyanogenic glycosides and furocoumarins in food is reported herein. Specifically, a literature search from 2011 to 2021 was carried out, selecting a total of 96 papers. Different approaches to sample preparation, chromatographic separation and detection mode are discussed. Particular attention is given to the analytical performance characteristics obtained in the validation process and the relevant application to real samples.https://www.mdpi.com/2072-6651/14/5/328natural toxinsfoodanalytical methodsliquid chromatography-mass spectrometrysimultaneous detection |
| spellingShingle | Annalisa De Girolamo Vincenzo Lippolis Michelangelo Pascale Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products Toxins natural toxins food analytical methods liquid chromatography-mass spectrometry simultaneous detection |
| title | Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products |
| title_full | Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products |
| title_fullStr | Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products |
| title_full_unstemmed | Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products |
| title_short | Overview of Recent Liquid Chromatography Mass Spectrometry-Based Methods for Natural Toxins Detection in Food Products |
| title_sort | overview of recent liquid chromatography mass spectrometry based methods for natural toxins detection in food products |
| topic | natural toxins food analytical methods liquid chromatography-mass spectrometry simultaneous detection |
| url | https://www.mdpi.com/2072-6651/14/5/328 |
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