Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia
Sacral neuromodulation (SNM) is a safe, efficacious, and minimally invasive advanced therapy that involves electrical stimulation to sacral nerve root to modulate neural pathway. Indications for SNM include symptoms of overactive bladder (OAB), urinary incontinence, urinary retention, urgency and...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2023-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/447644 |
| _version_ | 1797206230376120320 |
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| author | Mirko Bakula Dinko Hauptman Tvrtko Hudolin Sandra Nađ Škegro Katarina Ivana Tudor Branko Bakula Željko Kaštelan |
| author_facet | Mirko Bakula Dinko Hauptman Tvrtko Hudolin Sandra Nađ Škegro Katarina Ivana Tudor Branko Bakula Željko Kaštelan |
| author_sort | Mirko Bakula |
| collection | DOAJ |
| description | Sacral neuromodulation (SNM) is a safe, efficacious, and minimally invasive advanced
therapy that involves electrical stimulation to sacral nerve root to modulate neural pathway.
Indications for SNM include symptoms of overactive bladder (OAB), urinary incontinence, urinary
retention, urgency and frequency and, regarding bowel dysfunction, fecal incontinence . In Europe and
Canada, indication is also established for chronic constipation. The mechanism of action is still not fully
elucidated and complete understanding is yet to be determined. It is proposed that SNM modulates
neural circuits in both central and peripheral pathways, thus having an impact on the brain, as well as on
the bladder-targeting neuronal activity. Another possible significant effect on irregular bladder activity
is through inhibition of the bladder afferent pathways by stimulation of the pudendal nerve. Over the
past two decades, with more than 300 000 treated patients, SNM has confirmed its efficacy to relieve
refractory OAB symptoms, as well as urinary retention or fecal incontinence. First SNM applications in
Croatia were uneventful and we are glad to offer our patients this novel therapy in the future. |
| first_indexed | 2024-04-24T09:03:43Z |
| format | Article |
| id | doaj.art-2f18bd520f4c47eebb82f52d04c18bfc |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:03:43Z |
| publishDate | 2023-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-2f18bd520f4c47eebb82f52d04c18bfc2024-04-15T19:05:30ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512023-01-0162.Supplement 214314710.20471/acc.2023.62.s2.21Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in CroatiaMirko Bakula0Dinko Hauptman1Tvrtko Hudolin2Sandra Nađ Škegro3Katarina Ivana Tudor4Branko Bakula5Željko Kaštelan6Department of Urology, Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Urology, Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Urology, Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Urology, Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Neurology, Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Surgery, Sveti Duh University Hospital, Zagreb, CroatiaDepartment of Urology, Zagreb University Hospital Center, Zagreb, CroatiaSacral neuromodulation (SNM) is a safe, efficacious, and minimally invasive advanced therapy that involves electrical stimulation to sacral nerve root to modulate neural pathway. Indications for SNM include symptoms of overactive bladder (OAB), urinary incontinence, urinary retention, urgency and frequency and, regarding bowel dysfunction, fecal incontinence . In Europe and Canada, indication is also established for chronic constipation. The mechanism of action is still not fully elucidated and complete understanding is yet to be determined. It is proposed that SNM modulates neural circuits in both central and peripheral pathways, thus having an impact on the brain, as well as on the bladder-targeting neuronal activity. Another possible significant effect on irregular bladder activity is through inhibition of the bladder afferent pathways by stimulation of the pudendal nerve. Over the past two decades, with more than 300 000 treated patients, SNM has confirmed its efficacy to relieve refractory OAB symptoms, as well as urinary retention or fecal incontinence. First SNM applications in Croatia were uneventful and we are glad to offer our patients this novel therapy in the future.https://hrcak.srce.hr/file/447644Sacral neuromodulationOveractive bladderCroatia |
| spellingShingle | Mirko Bakula Dinko Hauptman Tvrtko Hudolin Sandra Nađ Škegro Katarina Ivana Tudor Branko Bakula Željko Kaštelan Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia Acta Clinica Croatica Sacral neuromodulation Overactive bladder Croatia |
| title | Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia |
| title_full | Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia |
| title_fullStr | Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia |
| title_full_unstemmed | Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia |
| title_short | Sacral Neuromodulation in Treating Overactive Bladder Patients – First-Time Application in Croatia |
| title_sort | sacral neuromodulation in treating overactive bladder patients first time application in croatia |
| topic | Sacral neuromodulation Overactive bladder Croatia |
| url | https://hrcak.srce.hr/file/447644 |
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