Depression in Parkinson Disease: Current Understanding and Treatment

Depression has a negative impact on activities of daily living, cognitive performance, and quality of life. Despite the high prevalence of depressive symptoms in Parkinson disease (PD), this important clinical feature is under-recognized by physicians. Effective diagnosis, assessment and treatment o...

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Main Authors: Pei-Hao Chen, Shih-Jung Cheng
Format: Article
Language:English
Published: Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) 2008-12-01
Series:International Journal of Gerontology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873959809700067
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author Pei-Hao Chen
Shih-Jung Cheng
author_facet Pei-Hao Chen
Shih-Jung Cheng
author_sort Pei-Hao Chen
collection DOAJ
description Depression has a negative impact on activities of daily living, cognitive performance, and quality of life. Despite the high prevalence of depressive symptoms in Parkinson disease (PD), this important clinical feature is under-recognized by physicians. Effective diagnosis, assessment and treatment of depression are, therefore, important aspects of PD management. In this article, we review the literature concerning depression associated with PD, paying specific attention to clinical presentation, diagnosis, etiology, and the principles of management and treatment. The efficacy and safety of antidepressants must rely on empiric assessments of known risks and putative benefits to guide treatment decisions.
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spelling doaj.art-2f19f51219244c74b4704084c9d353cf2022-12-22T00:24:04ZengTaiwan Society of Geriatric Emergency and Critical Medicine (TSGECM)International Journal of Gerontology1873-95982008-12-012417218210.1016/S1873-9598(09)70006-7Depression in Parkinson Disease: Current Understanding and TreatmentPei-Hao ChenShih-Jung ChengDepression has a negative impact on activities of daily living, cognitive performance, and quality of life. Despite the high prevalence of depressive symptoms in Parkinson disease (PD), this important clinical feature is under-recognized by physicians. Effective diagnosis, assessment and treatment of depression are, therefore, important aspects of PD management. In this article, we review the literature concerning depression associated with PD, paying specific attention to clinical presentation, diagnosis, etiology, and the principles of management and treatment. The efficacy and safety of antidepressants must rely on empiric assessments of known risks and putative benefits to guide treatment decisions.http://www.sciencedirect.com/science/article/pii/S1873959809700067antidepressive agentsanxietyneurogenic urinary bladderpsychotic disorderssleep disorders
spellingShingle Pei-Hao Chen
Shih-Jung Cheng
Depression in Parkinson Disease: Current Understanding and Treatment
International Journal of Gerontology
antidepressive agents
anxiety
neurogenic urinary bladder
psychotic disorders
sleep disorders
title Depression in Parkinson Disease: Current Understanding and Treatment
title_full Depression in Parkinson Disease: Current Understanding and Treatment
title_fullStr Depression in Parkinson Disease: Current Understanding and Treatment
title_full_unstemmed Depression in Parkinson Disease: Current Understanding and Treatment
title_short Depression in Parkinson Disease: Current Understanding and Treatment
title_sort depression in parkinson disease current understanding and treatment
topic antidepressive agents
anxiety
neurogenic urinary bladder
psychotic disorders
sleep disorders
url http://www.sciencedirect.com/science/article/pii/S1873959809700067
work_keys_str_mv AT peihaochen depressioninparkinsondiseasecurrentunderstandingandtreatment
AT shihjungcheng depressioninparkinsondiseasecurrentunderstandingandtreatment