Elevated serum Activin A in chronic obstructive pulmonary disease with skeletal muscle wasting

Elevated serum Activin A in chronic obstructive pulmonary disease with skeletal muscle wasting

OBJECTIVE: Muscle wasting contributes to the reduced quality of life and increased mortality in chronic obstructive pulmonary disease (COPD). Muscle atrophy in mice with cachexia was caused by Activin A binding to ActRIIB. The role of circulating Activin A leading to muscle atrophy in COPD remains e...

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Bibliographic Details
Main Authors: Guanghui Zhou, Xianhua Gui, Ruhua Chen, Xingli Fu, Xiuhai Ji, Hui Ding
Format: Article
Language:English
Published: Elsevier España
Series:Clinics
Subjects:
COPD
Skeletal Muscle
Activin A
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322019000100244&lng=en&tlng=en

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