Integrated analysis of clinical and genetic factors on the interindividual variation of warfarin anticoagulation efficacy in clinical practice

Integrated analysis of clinical and genetic factors on the interindividual variation of warfarin anticoagulation efficacy in clinical practice

Abstract Aim The anticoagulation effect of warfarin is usually evaluated by percentage of time in therapeutic range (PTTR), which is negatively correlated with the risk of warfarin adverse reactions. This study aimed to explore the effects of genetic and nongenetic factors on anticoagulation efficac...

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Bibliographic Details
Main Authors: Bao Sun, Siqing Ma, Feiyan Xiao, Jianquan Luo, Mouze Liu, Wenhui Liu, Zhiying Luo
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Warfarin
Polymorphism
PTTR
Efficacy
Pharmacogenomics
Online Access:https://doi.org/10.1186/s12872-023-03321-9

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