Locally advanced cancer of the tongue base: new method of surgical treatment

Introduction. Patients are characterized by locally advanced tumors in 70–80 % of cases at presentation, so possibility of cure and surgical treatment is limited. Total glossectomy, tongue base resection is associated with severe and permanent disability. Such surgical procedures lead to severe dysp...

Full description

Bibliographic Details
Main Authors: I. A. Zaderenko, A. M. Mudunov, S. Yu. Ivanov, R. I. Azizyan, A. A. Akhundov, S. B. Alieva, V. T. Tsiklauri, M. N. Narimanov, A. E. Kazimov, K. D. Il’kaev, A. V. Khromushina
Format: Article
Language:Russian
Published: ABV-press 2018-04-01
Series:Опухоли головы и шеи
Subjects:
Online Access:https://ogsh.abvpress.ru/jour/article/view/318
_version_ 1797876198478446592
author I. A. Zaderenko
A. M. Mudunov
S. Yu. Ivanov
R. I. Azizyan
A. A. Akhundov
S. B. Alieva
V. T. Tsiklauri
M. N. Narimanov
A. E. Kazimov
K. D. Il’kaev
A. V. Khromushina
author_facet I. A. Zaderenko
A. M. Mudunov
S. Yu. Ivanov
R. I. Azizyan
A. A. Akhundov
S. B. Alieva
V. T. Tsiklauri
M. N. Narimanov
A. E. Kazimov
K. D. Il’kaev
A. V. Khromushina
author_sort I. A. Zaderenko
collection DOAJ
description Introduction. Patients are characterized by locally advanced tumors in 70–80 % of cases at presentation, so possibility of cure and surgical treatment is limited. Total glossectomy, tongue base resection is associated with severe and permanent disability. Such surgical procedures lead to severe dysphagia, alalia and social maladjustment. Enumerated issues motivated us to develop new method of surgical treatment  of locally advanced base of tongue cancer.Objective is to introduce new opportunities of surgical treatment of locally advanced cancer of the tongue base.Materials and methods. Glossectomy is accomplished in 5 patients suffering from tongue cancer and admitted to N.N. Blokhin National Medical Research Center of Oncology. Swallowing and speech is preserved in all 5 cases.Results. The main advantage of the proposed method is that the cut out muscle flap has a different innervation from different cranial nerves involved in the rate of swallowing, so there is not just a mechanical movement of the epiglottis, but also the control of swallowing by the central nervous system. The reduction of injury and operation time in the proposed method is due to the fact that tissues directly contacting with the defect are used to preserve swallowing and speech. The proposed muscle flap has various sources of blood supply, which improves its nutrition and reduces the risk of complications, and healing occurs in a shorter time in comparison with the prototype. All of the above reduces the duration of hospitalization for an average of 7–9 days.Conclusion. The developed surgical technique allows to achieve early rehabilitation; patients are able to breathe effortlessly, swallow and speak. There is no need in permanent tracheostoma and percutaneous endoscopic gastrostomy tube. All patients remains socially active.
first_indexed 2024-04-10T01:58:22Z
format Article
id doaj.art-2f1da49ccd3a4e9f90497a3616e42378
institution Directory Open Access Journal
issn 2222-1468
2411-4634
language Russian
last_indexed 2024-04-10T01:58:22Z
publishDate 2018-04-01
publisher ABV-press
record_format Article
series Опухоли головы и шеи
spelling doaj.art-2f1da49ccd3a4e9f90497a3616e423782023-03-13T08:43:19ZrusABV-pressОпухоли головы и шеи2222-14682411-46342018-04-0181121610.17650/2222-1468-2018-8-1-12-16284Locally advanced cancer of the tongue base: new method of surgical treatmentI. A. Zaderenko0A. M. Mudunov1S. Yu. Ivanov2R. I. Azizyan3A. A. Akhundov4S. B. Alieva5V. T. Tsiklauri6M. N. Narimanov7A. E. Kazimov8K. D. Il’kaev9A. V. Khromushina10ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.Кафедра челюстно-лицевой хирургии и хирургической стоматологии ФГАОУ ВО «Российский университет дружбы народов».ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России.Кафедра челюстно-лицевой хирургии и хирургической стоматологии ФГАОУ ВО «Российский университет дружбы народов».Introduction. Patients are characterized by locally advanced tumors in 70–80 % of cases at presentation, so possibility of cure and surgical treatment is limited. Total glossectomy, tongue base resection is associated with severe and permanent disability. Such surgical procedures lead to severe dysphagia, alalia and social maladjustment. Enumerated issues motivated us to develop new method of surgical treatment  of locally advanced base of tongue cancer.Objective is to introduce new opportunities of surgical treatment of locally advanced cancer of the tongue base.Materials and methods. Glossectomy is accomplished in 5 patients suffering from tongue cancer and admitted to N.N. Blokhin National Medical Research Center of Oncology. Swallowing and speech is preserved in all 5 cases.Results. The main advantage of the proposed method is that the cut out muscle flap has a different innervation from different cranial nerves involved in the rate of swallowing, so there is not just a mechanical movement of the epiglottis, but also the control of swallowing by the central nervous system. The reduction of injury and operation time in the proposed method is due to the fact that tissues directly contacting with the defect are used to preserve swallowing and speech. The proposed muscle flap has various sources of blood supply, which improves its nutrition and reduces the risk of complications, and healing occurs in a shorter time in comparison with the prototype. All of the above reduces the duration of hospitalization for an average of 7–9 days.Conclusion. The developed surgical technique allows to achieve early rehabilitation; patients are able to breathe effortlessly, swallow and speak. There is no need in permanent tracheostoma and percutaneous endoscopic gastrostomy tube. All patients remains socially active.https://ogsh.abvpress.ru/jour/article/view/318местно-распространенный рак корня языкаглоссэктомияхирургическое лечение
spellingShingle I. A. Zaderenko
A. M. Mudunov
S. Yu. Ivanov
R. I. Azizyan
A. A. Akhundov
S. B. Alieva
V. T. Tsiklauri
M. N. Narimanov
A. E. Kazimov
K. D. Il’kaev
A. V. Khromushina
Locally advanced cancer of the tongue base: new method of surgical treatment
Опухоли головы и шеи
местно-распространенный рак корня языка
глоссэктомия
хирургическое лечение
title Locally advanced cancer of the tongue base: new method of surgical treatment
title_full Locally advanced cancer of the tongue base: new method of surgical treatment
title_fullStr Locally advanced cancer of the tongue base: new method of surgical treatment
title_full_unstemmed Locally advanced cancer of the tongue base: new method of surgical treatment
title_short Locally advanced cancer of the tongue base: new method of surgical treatment
title_sort locally advanced cancer of the tongue base new method of surgical treatment
topic местно-распространенный рак корня языка
глоссэктомия
хирургическое лечение
url https://ogsh.abvpress.ru/jour/article/view/318
work_keys_str_mv AT iazaderenko locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT ammudunov locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT syuivanov locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT riazizyan locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT aaakhundov locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT sbalieva locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT vttsiklauri locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT mnnarimanov locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT aekazimov locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT kdilkaev locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment
AT avkhromushina locallyadvancedcancerofthetonguebasenewmethodofsurgicaltreatment