A Novel Boron Lipid to Modify Liposomal Surfaces for Boron Neutron Capture Therapy

A Novel Boron Lipid to Modify Liposomal Surfaces for Boron Neutron Capture Therapy

Boron neutron capture therapy (BNCT) is a cancer treatment with clinically demonstrated efficacy using boronophenylalanine (BPA) and sodium mercaptododecaborate (BSH). However, tumor tissue selectivity of BSH and retention of BPA in tumor cells is a constant problem. To ensure boron accumulation and...

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Bibliographic Details
Main Authors: Makoto Shirakawa, Alexander Zaboronok, Kei Nakai, Yuhki Sato, Sho Kayaki, Tomonori Sakai, Takao Tsurubuchi, Fumiyo Yoshida, Takashi Nishiyama, Minoru Suzuki, Hisao Tomida, Akira Matsumura
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
boron neutron capture therapy
boron lipid
liposomes
boron drug
Online Access:https://www.mdpi.com/2073-4409/10/12/3421

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