Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

Abstract Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway. These results suggest that matrine has antivir...

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Bibliographic Details
Main Authors: Panpan Sun, Na Sun, Wei Yin, Yaogui Sun, Kuohai Fan, Jianhua Guo, Ajab Khan, Yongming He, Hongquan Li
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-019-0671-x

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