Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review
Pectin is a polymer with a core of alternating <i>α</i>-1,4-linked <span style="font-variant: small-caps;">d</span>-galacturonic acid and α-1,2-<span style="font-variant: small-caps;">l</span>-rhamnose units, as well as a vari...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-12-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/10/12/1407 |
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| author | Salima T. Minzanova Vladimir F. Mironov Daria M. Arkhipova Anna V. Khabibullina Lubov G. Mironova Yulia M. Zakirova Vasili A. Milyukov |
| author_facet | Salima T. Minzanova Vladimir F. Mironov Daria M. Arkhipova Anna V. Khabibullina Lubov G. Mironova Yulia M. Zakirova Vasili A. Milyukov |
| author_sort | Salima T. Minzanova |
| collection | DOAJ |
| description | Pectin is a polymer with a core of alternating <i>α</i>-1,4-linked <span style="font-variant: small-caps;">d</span>-galacturonic acid and α-1,2-<span style="font-variant: small-caps;">l</span>-rhamnose units, as well as a variety of neutral sugars such as arabinose, galactose, and lesser amounts of other sugars. Currently, native pectins have been compared to modified ones due to the development of natural medicines and health products. In this review, the results of a study of the bioactivity of pectic polysaccharides, including its various pharmacological applications, such as its immunoregulatory, anti-inflammatory, hypoglycemic, antibacterial, antioxidant and antitumor activities, have been summarized. The potential of pectins to contribute to the enhancement of drug delivery systems has been observed. |
| first_indexed | 2024-04-12T07:10:18Z |
| format | Article |
| id | doaj.art-2f268ee0d3de45a8b5aa7763b210ea2e |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-04-12T07:10:18Z |
| publishDate | 2018-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-2f268ee0d3de45a8b5aa7763b210ea2e2022-12-22T03:42:39ZengMDPI AGPolymers2073-43602018-12-011012140710.3390/polym10121407polym10121407Biological Activity and Pharmacological Application of Pectic Polysaccharides: A ReviewSalima T. Minzanova0Vladimir F. Mironov1Daria M. Arkhipova2Anna V. Khabibullina3Lubov G. Mironova4Yulia M. Zakirova5Vasili A. Milyukov6Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan 420088, RussiaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan 420088, RussiaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan 420088, RussiaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan 420088, RussiaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan 420088, RussiaKazan (Volga region) Federal University, Kazan University, KFU, Kazan 420008, RussiaArbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Kazan 420088, RussiaPectin is a polymer with a core of alternating <i>α</i>-1,4-linked <span style="font-variant: small-caps;">d</span>-galacturonic acid and α-1,2-<span style="font-variant: small-caps;">l</span>-rhamnose units, as well as a variety of neutral sugars such as arabinose, galactose, and lesser amounts of other sugars. Currently, native pectins have been compared to modified ones due to the development of natural medicines and health products. In this review, the results of a study of the bioactivity of pectic polysaccharides, including its various pharmacological applications, such as its immunoregulatory, anti-inflammatory, hypoglycemic, antibacterial, antioxidant and antitumor activities, have been summarized. The potential of pectins to contribute to the enhancement of drug delivery systems has been observed.https://www.mdpi.com/2073-4360/10/12/1407pectinmodified pectinbiological activitydrug deliverypharmaceutical |
| spellingShingle | Salima T. Minzanova Vladimir F. Mironov Daria M. Arkhipova Anna V. Khabibullina Lubov G. Mironova Yulia M. Zakirova Vasili A. Milyukov Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review Polymers pectin modified pectin biological activity drug delivery pharmaceutical |
| title | Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review |
| title_full | Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review |
| title_fullStr | Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review |
| title_full_unstemmed | Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review |
| title_short | Biological Activity and Pharmacological Application of Pectic Polysaccharides: A Review |
| title_sort | biological activity and pharmacological application of pectic polysaccharides a review |
| topic | pectin modified pectin biological activity drug delivery pharmaceutical |
| url | https://www.mdpi.com/2073-4360/10/12/1407 |
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