Dyslipidemia in Type 2 Diabetes mellitus

<p><strong>Background:</strong> In type 2 diabetes mellitus lipid abnormalities are very common and is associated with increased risk of cardiovascular diseases.  This study was conducted to find association of type 2 diabetes and dyslipidemia.</p><p><strong>Mater...

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Main Authors: Subarna Dhoj Thapa, Shiva Raj K.C, Santosh Gautam, Deepika Gyawali
Format: Article
Language:English
Published: Association of Clinical Pathologists of Nepal 2017-09-01
Series:Journal of Pathology of Nepal
Subjects:
Online Access:http://www.nepjol.info/index.php/JPN/article/view/17978
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author Subarna Dhoj Thapa
Shiva Raj K.C
Santosh Gautam
Deepika Gyawali
author_facet Subarna Dhoj Thapa
Shiva Raj K.C
Santosh Gautam
Deepika Gyawali
author_sort Subarna Dhoj Thapa
collection DOAJ
description <p><strong>Background:</strong> In type 2 diabetes mellitus lipid abnormalities are very common and is associated with increased risk of cardiovascular diseases.  This study was conducted to find association of type 2 diabetes and dyslipidemia.</p><p><strong>Materials and Methods:</strong> This cross-sectional study was conducted at KISTMCTH. All the necessary data of patient with type 2 diabetes in the period between December 2016 and May 2017 were studied.</p><p><strong>Results:</strong> Out of 199 patients with diabetes mellitus 30.7% had total cholesterol &gt;200 mg/dl, 64.4% had elevated low density lipoprotein, 53.77% patient had elevated triglyceride and 64% patients had low high density lipoprotein level. Cholesterol showed significant correlation with triglyceride (P &lt; 0.001), low density lipoprotein (P &lt; 0.001). Triglyceride showed a significant negative correlation with high density lipoprotein (P &lt; 0.01), while a highly significant positive correlation was observed with cholesterol and high density lipoprotein (P &lt; 0.001).</p><p><strong>Conclusion:</strong> Diabetes is associated with high incidence of dyslipidemia with elevated level of low density lipoprotein, cholesterol and triglyceride.</p>
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spelling doaj.art-2f29ad3500764d229a49a00d54b4c1312022-12-22T02:29:10ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082017-09-01721149115410.3126/jpn.v7i2.1797813976Dyslipidemia in Type 2 Diabetes mellitusSubarna Dhoj Thapa0Shiva Raj K.C1Santosh Gautam2Deepika Gyawali3KIST Medical College and Teaching HospitalKIST Medical College and Teaching HospitalKIST Medical College and Teaching HospitalKIST Medical College and Teaching Hospital<p><strong>Background:</strong> In type 2 diabetes mellitus lipid abnormalities are very common and is associated with increased risk of cardiovascular diseases.  This study was conducted to find association of type 2 diabetes and dyslipidemia.</p><p><strong>Materials and Methods:</strong> This cross-sectional study was conducted at KISTMCTH. All the necessary data of patient with type 2 diabetes in the period between December 2016 and May 2017 were studied.</p><p><strong>Results:</strong> Out of 199 patients with diabetes mellitus 30.7% had total cholesterol &gt;200 mg/dl, 64.4% had elevated low density lipoprotein, 53.77% patient had elevated triglyceride and 64% patients had low high density lipoprotein level. Cholesterol showed significant correlation with triglyceride (P &lt; 0.001), low density lipoprotein (P &lt; 0.001). Triglyceride showed a significant negative correlation with high density lipoprotein (P &lt; 0.01), while a highly significant positive correlation was observed with cholesterol and high density lipoprotein (P &lt; 0.001).</p><p><strong>Conclusion:</strong> Diabetes is associated with high incidence of dyslipidemia with elevated level of low density lipoprotein, cholesterol and triglyceride.</p>http://www.nepjol.info/index.php/JPN/article/view/17978CholesterolDiabetesGlucoseLipid profileLipoproteinTriglyceride
spellingShingle Subarna Dhoj Thapa
Shiva Raj K.C
Santosh Gautam
Deepika Gyawali
Dyslipidemia in Type 2 Diabetes mellitus
Journal of Pathology of Nepal
Cholesterol
Diabetes
Glucose
Lipid profile
Lipoprotein
Triglyceride
title Dyslipidemia in Type 2 Diabetes mellitus
title_full Dyslipidemia in Type 2 Diabetes mellitus
title_fullStr Dyslipidemia in Type 2 Diabetes mellitus
title_full_unstemmed Dyslipidemia in Type 2 Diabetes mellitus
title_short Dyslipidemia in Type 2 Diabetes mellitus
title_sort dyslipidemia in type 2 diabetes mellitus
topic Cholesterol
Diabetes
Glucose
Lipid profile
Lipoprotein
Triglyceride
url http://www.nepjol.info/index.php/JPN/article/view/17978
work_keys_str_mv AT subarnadhojthapa dyslipidemiaintype2diabetesmellitus
AT shivarajkc dyslipidemiaintype2diabetesmellitus
AT santoshgautam dyslipidemiaintype2diabetesmellitus
AT deepikagyawali dyslipidemiaintype2diabetesmellitus