Budesonide Analogues Preserve Stem Cell Pluripotency and Delay 3D Gastruloid Development

Budesonide Analogues Preserve Stem Cell Pluripotency and Delay 3D Gastruloid Development

Small molecules that can modulate or stabilize cell–cell interactions are valuable tools for investigating the impact of collective cell behavior on various biological processes such as development/morphogenesis, tissue regeneration and cancer progression. Recently, we showed that budesonide, a gluc...

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Bibliographic Details
Main Authors: Filomena Amoroso, Eduardo Ibello, Federica Saracino, Federica Cermola, Giovanna Ponticelli, Enrica Scalera, Francesca Ricci, Gino Villetti, Gilda Cobellis, Gabriella Minchiotti, Eduardo Jorge Patriarca, Dario De Cesare, Cristina D’Aniello
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceutics
Subjects:
drug toxicity
budesonide analogues
stem cells
pluripotency exit
3D gastruloids
Online Access:https://www.mdpi.com/1999-4923/15/7/1897

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