Generation of three iPSC lines from different types of pediatric acute leukemia patients
Leukemia is the most common malignant tumor in childhood. The pathogenesis of leukemia is still unclear. Therefore, it is imperative to establish effective disease models. In our study, we reprogrammed different types of pediatric acute leukemia cells into iPSCs using CytoTune®Sendai virus. All gene...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-08-01
|
| Series: | Stem Cell Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S187350612100307X |
| _version_ | 1831725501722394624 |
|---|---|
| author | Yang Li Yingwen Zhang Ting Li Xiang Wang Weiqiao Bao Jun Huang Yani Ma Shanshan Li Siqi wang Yi Yang Yanfeng Liu Yijin Gao Haizhong Feng Yanxin Li |
| author_facet | Yang Li Yingwen Zhang Ting Li Xiang Wang Weiqiao Bao Jun Huang Yani Ma Shanshan Li Siqi wang Yi Yang Yanfeng Liu Yijin Gao Haizhong Feng Yanxin Li |
| author_sort | Yang Li |
| collection | DOAJ |
| description | Leukemia is the most common malignant tumor in childhood. The pathogenesis of leukemia is still unclear. Therefore, it is imperative to establish effective disease models. In our study, we reprogrammed different types of pediatric acute leukemia cells into iPSCs using CytoTune®Sendai virus. All generated iPSCs maintained pluripotency and spontaneous in vivo differentiation capacity. |
| first_indexed | 2024-12-21T04:40:50Z |
| format | Article |
| id | doaj.art-2f2d4c58748540478502f4dd759bc0b1 |
| institution | Directory Open Access Journal |
| issn | 1873-5061 |
| language | English |
| last_indexed | 2024-12-21T04:40:50Z |
| publishDate | 2021-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Stem Cell Research |
| spelling | doaj.art-2f2d4c58748540478502f4dd759bc0b12022-12-21T19:15:42ZengElsevierStem Cell Research1873-50612021-08-0155102460Generation of three iPSC lines from different types of pediatric acute leukemia patientsYang Li0Yingwen Zhang1Ting Li2Xiang Wang3Weiqiao Bao4Jun Huang5Yani Ma6Shanshan Li7Siqi wang8Yi Yang9Yanfeng Liu10Yijin Gao11Haizhong Feng12Yanxin Li13Department of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, ChinaDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, Shandong 250012, ChinaDepartment of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, China; Corresponding authors.State Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China; Corresponding authors.Department of Hematology & Oncology, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology & Oncology, Shanghai 200127, China; Corresponding authors.Leukemia is the most common malignant tumor in childhood. The pathogenesis of leukemia is still unclear. Therefore, it is imperative to establish effective disease models. In our study, we reprogrammed different types of pediatric acute leukemia cells into iPSCs using CytoTune®Sendai virus. All generated iPSCs maintained pluripotency and spontaneous in vivo differentiation capacity.http://www.sciencedirect.com/science/article/pii/S187350612100307X |
| spellingShingle | Yang Li Yingwen Zhang Ting Li Xiang Wang Weiqiao Bao Jun Huang Yani Ma Shanshan Li Siqi wang Yi Yang Yanfeng Liu Yijin Gao Haizhong Feng Yanxin Li Generation of three iPSC lines from different types of pediatric acute leukemia patients Stem Cell Research |
| title | Generation of three iPSC lines from different types of pediatric acute leukemia patients |
| title_full | Generation of three iPSC lines from different types of pediatric acute leukemia patients |
| title_fullStr | Generation of three iPSC lines from different types of pediatric acute leukemia patients |
| title_full_unstemmed | Generation of three iPSC lines from different types of pediatric acute leukemia patients |
| title_short | Generation of three iPSC lines from different types of pediatric acute leukemia patients |
| title_sort | generation of three ipsc lines from different types of pediatric acute leukemia patients |
| url | http://www.sciencedirect.com/science/article/pii/S187350612100307X |
| work_keys_str_mv | AT yangli generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT yingwenzhang generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT tingli generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT xiangwang generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT weiqiaobao generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT junhuang generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT yanima generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT shanshanli generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT siqiwang generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT yiyang generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT yanfengliu generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT yijingao generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT haizhongfeng generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients AT yanxinli generationofthreeipsclinesfromdifferenttypesofpediatricacuteleukemiapatients |