Deep learning-augmented T-junction droplet generation

Summary: Droplet generation technology has become increasingly important in a wide range of applications, including biotechnology and chemical synthesis. T-junction channels are commonly used for droplet generation due to their integration capability of a larger number of droplet generators in a com...

Description complète

Détails bibliographiques
Auteurs principaux: Abdollah Ahmadpour, Mostafa Shojaeian, Savas Tasoglu
Format: Article
Langue:English
Publié: Elsevier 2024-04-01
Collection:iScience
Sujets:
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2589004224005479
Description
Résumé:Summary: Droplet generation technology has become increasingly important in a wide range of applications, including biotechnology and chemical synthesis. T-junction channels are commonly used for droplet generation due to their integration capability of a larger number of droplet generators in a compact space. In this study, a finite element analysis (FEA) approach is employed to simulate droplet production and its dynamic regimes in a T-junction configuration and collect data for post-processing analysis. Next, image analysis was performed to calculate the droplet length and determine the droplet generation regime. Furthermore, machine learning (ML) and deep learning (DL) algorithms were applied to estimate outputs through examination of input parameters within the simulation range. At the end, a graphical user interface (GUI) was developed for estimation of the droplet characteristics based on inputs, enabling the users to preselect their designs with comparable microfluidic configurations within the studied range.
ISSN:2589-0042