Analysis of Cerebral Small Vessel Changes in AD Model Mice

Analysis of Cerebral Small Vessel Changes in AD Model Mice

Amyloid β (Aβ) peptide is deposited in the brains of sporadic Alzheimer’s disease (AD) due to impaired vessel-dependent clearance. To understand the mechanisms, we investigated time-dependent cerebrovascular changes in AD model mice. Cerebrovascular and other pathological changes were analyzed in AD...

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Bibliographic Details
Main Authors: Abu Zaffar Shibly, Abdullah Md. Sheikh, Makoto Michikawa, Shatera Tabassum, Abul Kalam Azad, Xiaojing Zhou, Yuchi Zhang, Shozo Yano, Atsushi Nagai
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
Alzheimer’s disease (AD)
APP transgenic mouse
amyloid β
vessel leakage
blood brain barrier (BBB)
Online Access:https://www.mdpi.com/2227-9059/11/1/50

Internet

https://www.mdpi.com/2227-9059/11/1/50

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