The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case Report

Background: Primary non-Hodgkin breast lymphoma is a rare pathology, representing 0.5 percent of malignant breast tumors. Case Presentation: Here, we report a 54-year-old female presenting a mass in the left breast diagnosed by needle biopsy and IHC as a diffuse large B-cell lymphoma (DLBCL). Radiat...

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Main Authors: Saeed Karimkhani Zandi, Fatemeh Heidari
Format: Article
Language:English
Published: Kaviani Breast Disease Institute 2017-12-01
Series:Archives of Breast Cancer
Subjects:
Online Access:https://archbreastcancer.com/index.php/abc/article/view/148
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author Saeed Karimkhani Zandi
Fatemeh Heidari
author_facet Saeed Karimkhani Zandi
Fatemeh Heidari
author_sort Saeed Karimkhani Zandi
collection DOAJ
description Background: Primary non-Hodgkin breast lymphoma is a rare pathology, representing 0.5 percent of malignant breast tumors. Case Presentation: Here, we report a 54-year-old female presenting a mass in the left breast diagnosed by needle biopsy and IHC as a diffuse large B-cell lymphoma (DLBCL). Radiation therapy with conventional fields was applied for whole breast irradiation after the patient received 6 courses of R-CHOP (Rituximab plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone) chemotherapy. At the follow-up period 11 months after radiation therapy, no morbidities occurred and the patient is surviving with no evidence of disease. Conclusions: The common treatments for breast lymphomas are surgery, radiation therapy, and chemotherapy. Although no agreement has been reached on the best therapy for primary breast lymphomas, these methods are commonly applied alone or in combination. It seems that R-CHOP combined with radiation therapy regimen could be an important treatment modality in avoiding unnecessary surgery.
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spelling doaj.art-2f32c8fec35b4615bb98b6a41eb225442022-12-22T01:26:24ZengKaviani Breast Disease InstituteArchives of Breast Cancer2383-04332017-12-014410.19187/abc.201744141-145The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case ReportSaeed Karimkhani Zandi0Fatemeh Heidari1Radiation Oncology Department, Sadra Oncology Center, Qom, IranAnatomy Department, Qom University of medical sciences, Qom, IranBackground: Primary non-Hodgkin breast lymphoma is a rare pathology, representing 0.5 percent of malignant breast tumors. Case Presentation: Here, we report a 54-year-old female presenting a mass in the left breast diagnosed by needle biopsy and IHC as a diffuse large B-cell lymphoma (DLBCL). Radiation therapy with conventional fields was applied for whole breast irradiation after the patient received 6 courses of R-CHOP (Rituximab plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone) chemotherapy. At the follow-up period 11 months after radiation therapy, no morbidities occurred and the patient is surviving with no evidence of disease. Conclusions: The common treatments for breast lymphomas are surgery, radiation therapy, and chemotherapy. Although no agreement has been reached on the best therapy for primary breast lymphomas, these methods are commonly applied alone or in combination. It seems that R-CHOP combined with radiation therapy regimen could be an important treatment modality in avoiding unnecessary surgery.https://archbreastcancer.com/index.php/abc/article/view/148Breast lymphomaPrimary breast lymphoma (PBL)Diffuse large B-cell lymphoma (DLBCL)
spellingShingle Saeed Karimkhani Zandi
Fatemeh Heidari
The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case Report
Archives of Breast Cancer
Breast lymphoma
Primary breast lymphoma (PBL)
Diffuse large B-cell lymphoma (DLBCL)
title The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case Report
title_full The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case Report
title_fullStr The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case Report
title_full_unstemmed The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case Report
title_short The Bench of Primary Breast Lymphoma Treatment: A Review of the Literature and a Case Report
title_sort bench of primary breast lymphoma treatment a review of the literature and a case report
topic Breast lymphoma
Primary breast lymphoma (PBL)
Diffuse large B-cell lymphoma (DLBCL)
url https://archbreastcancer.com/index.php/abc/article/view/148
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