Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension
<p><strong>Aim</strong>. To study the prevalence of renal and renovascular disorders in the development and progression of primary arterial hypertension (HT) resistant to combination antihypertensive therapy (AHT) in cardiac and therapeutic patients of general hospital.</p>&l...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Столичная издательская компания
2015-12-01
|
| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | http://www.rpcardio.ru/jour/article/view/437 |
| _version_ | 1797723244922404864 |
|---|---|
| author | N. V. Teplova V. A. Lyusov R. G. Oganov E. M. Evsikov R. A. Sharipov M. H. Zhapoeva E. G. Kurumlidu |
| author_facet | N. V. Teplova V. A. Lyusov R. G. Oganov E. M. Evsikov R. A. Sharipov M. H. Zhapoeva E. G. Kurumlidu |
| author_sort | N. V. Teplova |
| collection | DOAJ |
| description | <p><strong>Aim</strong>. To study the prevalence of renal and renovascular disorders in the development and progression of primary arterial hypertension (HT) resistant to combination antihypertensive therapy (AHT) in cardiac and therapeutic patients of general hospital.</p><p><strong>Material and methods.</strong> 286 patients with essential HT stages 1-3, including 105 patients with stages 2-3 with the signs of treatment resistance were included into the study. All patients were treated with personalized AHT in accordance with current guidelines for the management of HT. Laboratory and instrumental assessment of a functional status of kidneys was performed.</p><p><strong>Results.</strong> A group of patients with resistant HT made 36.7% of the total number of examined patients. The most significant distinction in patients with resistant HT was a high incidence of changes in renal vessels and infrarenal aorta. Deformation of the abdominal aorta (9.7%), renal arteries tortuosity (7.3%), vasourethral conflict (4.8%) were detected in this group significantly more often.</p><p><strong>Conclusion.</strong> Congenital and acquired lesions of renal arteries are detected several times more often in patients with resistant essential HT.</p> |
| first_indexed | 2024-03-12T09:59:08Z |
| format | Article |
| id | doaj.art-2f36d36ff88a4a4192959d48aed5de4c |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-03-12T09:59:08Z |
| publishDate | 2015-12-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-2f36d36ff88a4a4192959d48aed5de4c2023-09-02T11:49:33ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-0111659059410.1234/1819-6446-2015-6-590-594437Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertensionN. V. Teplova0V. A. Lyusov1R. G. Oganov2E. M. Evsikov3R. A. Sharipov4M. H. Zhapoeva5E. G. Kurumlidu6Кафедра госпитальной терапии №1 лечебного факультета Российского национального исследовательского медицинского университета им. Н.И. Пирогова. 117437 Москва, улица Островитянова, 1Кафедра госпитальной терапии №1 лечебного факультета Российского национального исследовательского медицинского университета им. Н.И. Пирогова. 117437 Москва, улица Островитянова, 1Государственный научно-исследовательский центр профилактической медицины 101990 Москва, Петроверигский пер., 10Кафедра госпитальной терапии №1 лечебного факультета Российского национального исследовательского медицинского университета им. Н.И. Пирогова. 117437 Москва, улица Островитянова, 1Кафедра госпитальной терапии №1 лечебного факультета Российского национального исследовательского медицинского университета им. Н.И. Пирогова. 117437 Москва, улица Островитянова, 1Кафедра госпитальной терапии №1 лечебного факультета Российского национального исследовательского медицинского университета им. Н.И. Пирогова. 117437 Москва, улица Островитянова, 1Кафедра госпитальной терапии №1 лечебного факультета Российского национального исследовательского медицинского университета им. Н.И. Пирогова. 117437 Москва, улица Островитянова, 1<p><strong>Aim</strong>. To study the prevalence of renal and renovascular disorders in the development and progression of primary arterial hypertension (HT) resistant to combination antihypertensive therapy (AHT) in cardiac and therapeutic patients of general hospital.</p><p><strong>Material and methods.</strong> 286 patients with essential HT stages 1-3, including 105 patients with stages 2-3 with the signs of treatment resistance were included into the study. All patients were treated with personalized AHT in accordance with current guidelines for the management of HT. Laboratory and instrumental assessment of a functional status of kidneys was performed.</p><p><strong>Results.</strong> A group of patients with resistant HT made 36.7% of the total number of examined patients. The most significant distinction in patients with resistant HT was a high incidence of changes in renal vessels and infrarenal aorta. Deformation of the abdominal aorta (9.7%), renal arteries tortuosity (7.3%), vasourethral conflict (4.8%) were detected in this group significantly more often.</p><p><strong>Conclusion.</strong> Congenital and acquired lesions of renal arteries are detected several times more often in patients with resistant essential HT.</p>http://www.rpcardio.ru/jour/article/view/437резистентная артериальная гипертензиязаболевания почеквазоренальные поражения |
| spellingShingle | N. V. Teplova V. A. Lyusov R. G. Oganov E. M. Evsikov R. A. Sharipov M. H. Zhapoeva E. G. Kurumlidu Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension Рациональная фармакотерапия в кардиологии резистентная артериальная гипертензия заболевания почек вазоренальные поражения |
| title | Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension |
| title_full | Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension |
| title_fullStr | Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension |
| title_full_unstemmed | Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension |
| title_short | Nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension |
| title_sort | nephrogenic factors of resistance to antihypertensive treatment in patients with essential hypertension |
| topic | резистентная артериальная гипертензия заболевания почек вазоренальные поражения |
| url | http://www.rpcardio.ru/jour/article/view/437 |
| work_keys_str_mv | AT nvteplova nephrogenicfactorsofresistancetoantihypertensivetreatmentinpatientswithessentialhypertension AT valyusov nephrogenicfactorsofresistancetoantihypertensivetreatmentinpatientswithessentialhypertension AT rgoganov nephrogenicfactorsofresistancetoantihypertensivetreatmentinpatientswithessentialhypertension AT emevsikov nephrogenicfactorsofresistancetoantihypertensivetreatmentinpatientswithessentialhypertension AT rasharipov nephrogenicfactorsofresistancetoantihypertensivetreatmentinpatientswithessentialhypertension AT mhzhapoeva nephrogenicfactorsofresistancetoantihypertensivetreatmentinpatientswithessentialhypertension AT egkurumlidu nephrogenicfactorsofresistancetoantihypertensivetreatmentinpatientswithessentialhypertension |