Extraskeletal Myxoid Chondrosarcoma: Clinical and Molecular Characteristics and Outcomes of Patients Treated at Two Institutions

Extraskeletal Myxoid Chondrosarcoma: Clinical and Molecular Characteristics and Outcomes of Patients Treated at Two Institutions

Background: Extraskeletal myxoid chondrosarcoma (EMC) is a rare subtype of STS, which usually arises in extremities. It carries reciprocal translocations involving the NR4A3 gene. It displays an indolent behavior, but studies with long follow-up showed a high proportion of local and distant recurren...

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Main Authors: Benedetta Chiusole, Axel Le Cesne, Marco Rastrelli, Marco Maruzzo, Martina Lorenzi, Rocco Cappellesso, Paolo Del Fiore, Silvia Imbevaro, Marta Sbaraglia, Philippe Terrier, Pietro Ruggieri, Angelo Paolo Dei Tos, Carlo Riccardo Rossi, Vittorina Zagonel, Antonella Brunello
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
extrascheletal myxoid chondrosarcoma
anthracycline
NR4A3
drug holiday
chemotherapy (CHT)
surgery
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00828/full

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