Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatine

Agomelatine, a MT1 (Melatonin) and MT2 receptor agonist and 5-HT2C (5-Hidroksitriptamin)  antagonist, is an antidepressant agent used in the treatment of major depressive disorders. Intraocular pressure lowering effect of melatonin and its analogues have been demonstrated in a few experimental studi...

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Main Authors: Mehmet Emin Demirkol, Mahmut Onur Karaytuğ, Lut Tamam
Format: Article
Language:English
Published: Cukurova University 2019-12-01
Series:Cukurova Medical Journal
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/778048
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author Mehmet Emin Demirkol
Mahmut Onur Karaytuğ
Lut Tamam
author_facet Mehmet Emin Demirkol
Mahmut Onur Karaytuğ
Lut Tamam
author_sort Mehmet Emin Demirkol
collection DOAJ
description Agomelatine, a MT1 (Melatonin) and MT2 receptor agonist and 5-HT2C (5-Hidroksitriptamin)  antagonist, is an antidepressant agent used in the treatment of major depressive disorders. Intraocular pressure lowering effect of melatonin and its analogues have been demonstrated in a few experimental studies. In the present case report, we have documented the reversal of angle closure glaucoma by oral agomelatine in a patient with major depressive disorder under selective serotonine reuptake inhibitor treatment.  The patient, who had previously been diagnosed with glaucoma, was also receiving antiglaucomatous treatment.
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spelling doaj.art-2f3ace2aa610484ca9fb02fecf8f25532023-02-15T16:10:11ZengCukurova UniversityCukurova Medical Journal2602-30402019-12-014441520152310.17826/cumj.57218648Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatineMehmet Emin DemirkolMahmut Onur KaraytuğLut TamamAgomelatine, a MT1 (Melatonin) and MT2 receptor agonist and 5-HT2C (5-Hidroksitriptamin)  antagonist, is an antidepressant agent used in the treatment of major depressive disorders. Intraocular pressure lowering effect of melatonin and its analogues have been demonstrated in a few experimental studies. In the present case report, we have documented the reversal of angle closure glaucoma by oral agomelatine in a patient with major depressive disorder under selective serotonine reuptake inhibitor treatment.  The patient, who had previously been diagnosed with glaucoma, was also receiving antiglaucomatous treatment.https://dergipark.org.tr/tr/download/article-file/778048agomelatineangle closure glaucoma
spellingShingle Mehmet Emin Demirkol
Mahmut Onur Karaytuğ
Lut Tamam
Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatine
Cukurova Medical Journal
agomelatine
angle closure glaucoma
title Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatine
title_full Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatine
title_fullStr Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatine
title_full_unstemmed Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatine
title_short Acute angle closure glaucoma induced by selective serotonin reuptake inhibitor, and reversed by agomelatine
title_sort acute angle closure glaucoma induced by selective serotonin reuptake inhibitor and reversed by agomelatine
topic agomelatine
angle closure glaucoma
url https://dergipark.org.tr/tr/download/article-file/778048
work_keys_str_mv AT mehmetemindemirkol acuteangleclosureglaucomainducedbyselectiveserotoninreuptakeinhibitorandreversedbyagomelatine
AT mahmutonurkaraytug acuteangleclosureglaucomainducedbyselectiveserotoninreuptakeinhibitorandreversedbyagomelatine
AT luttamam acuteangleclosureglaucomainducedbyselectiveserotoninreuptakeinhibitorandreversedbyagomelatine