Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review
Hypersensitivity pneumonitis (HP) is characterized by inflammation of the lung parenchyma that is induced by exposure to an inhaled organic antigen. We present a case of recurrent, acute HP caused by repeated transient exposure to a down sleeping bag in a patient with a family history of chronic bir...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-01-01
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| Series: | Respiratory Medicine Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007117303258 |
| _version_ | 1819107233390133248 |
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| author | Tiffany Winstone Cameron J. Hague Andrew Churg Joanne L. Wright Robert Schellenberg Chris Ryerson |
| author_facet | Tiffany Winstone Cameron J. Hague Andrew Churg Joanne L. Wright Robert Schellenberg Chris Ryerson |
| author_sort | Tiffany Winstone |
| collection | DOAJ |
| description | Hypersensitivity pneumonitis (HP) is characterized by inflammation of the lung parenchyma that is induced by exposure to an inhaled organic antigen. We present a case of recurrent, acute HP caused by repeated transient exposure to a down sleeping bag in a patient with a family history of chronic bird-associated hypersensitivity pneumonitis. The patient's recurrent symptoms, changes in physiology, and radiographic findings coincided with repeated exposure to this source. It was later confirmed that the patient's sister had also developed chronic HP from recurrent exposure to household birds. This case highlights recent studies implicating gene-exposure interactions in the development of HP. Keywords: Hypersensitivity pneumonitis, Familial hypersensitivity pneumonitis, Organic antigen, Interstitial lung disease |
| first_indexed | 2024-12-22T02:50:47Z |
| format | Article |
| id | doaj.art-2f3ae17ebbe541a4b9ca71a6e8cc5b08 |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-22T02:50:47Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-2f3ae17ebbe541a4b9ca71a6e8cc5b082022-12-21T18:41:24ZengElsevierRespiratory Medicine Case Reports2213-00712018-01-0124173175Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature reviewTiffany Winstone0Cameron J. Hague1Andrew Churg2Joanne L. Wright3Robert Schellenberg4Chris Ryerson5Department of Medicine, University of British Columbia, Vancouver, Canada; Centre for Heart Lung Innovation, University of British Columbia, Vancouver, Canada; Corresponding author. Department of Medicine, University of British Columbia – St. Paul's Hospital, 1081 Burrard St, Ward 8B, Vancouver, V6Z 1Y6, Canada.Department of Radiology, University of British Columbia, Vancouver, CanadaDepartment of Pathology, University of British Columbia, Vancouver, CanadaDepartment of Pathology, University of British Columbia, Vancouver, CanadaDepartment of Medicine, University of British Columbia, Vancouver, Canada; Centre for Heart Lung Innovation, University of British Columbia, Vancouver, CanadaDepartment of Medicine, University of British Columbia, Vancouver, Canada; Centre for Heart Lung Innovation, University of British Columbia, Vancouver, CanadaHypersensitivity pneumonitis (HP) is characterized by inflammation of the lung parenchyma that is induced by exposure to an inhaled organic antigen. We present a case of recurrent, acute HP caused by repeated transient exposure to a down sleeping bag in a patient with a family history of chronic bird-associated hypersensitivity pneumonitis. The patient's recurrent symptoms, changes in physiology, and radiographic findings coincided with repeated exposure to this source. It was later confirmed that the patient's sister had also developed chronic HP from recurrent exposure to household birds. This case highlights recent studies implicating gene-exposure interactions in the development of HP. Keywords: Hypersensitivity pneumonitis, Familial hypersensitivity pneumonitis, Organic antigen, Interstitial lung diseasehttp://www.sciencedirect.com/science/article/pii/S2213007117303258 |
| spellingShingle | Tiffany Winstone Cameron J. Hague Andrew Churg Joanne L. Wright Robert Schellenberg Chris Ryerson Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review Respiratory Medicine Case Reports |
| title | Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review |
| title_full | Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review |
| title_fullStr | Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review |
| title_full_unstemmed | Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review |
| title_short | Biopsy-proven recurrent, acute, familial hypersensitivity pneumonitis: A case report and literature review |
| title_sort | biopsy proven recurrent acute familial hypersensitivity pneumonitis a case report and literature review |
| url | http://www.sciencedirect.com/science/article/pii/S2213007117303258 |
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