Functional intraepithelial lymphocyte changes in inflammatory bowel disease and spondyloarthritis have disease specific correlations with intestinal microbiota

Functional intraepithelial lymphocyte changes in inflammatory bowel disease and spondyloarthritis have disease specific correlations with intestinal microbiota

Abstract Background Dysbiosis occurs in spondyloarthritis (SpA) and inflammatory bowel disease (IBD), which is subdivided into Crohn’s disease (CD) and ulcerative colitis (UC). The immunologic consequences of alterations in microbiota, however, have not been defined. Intraepithelial lymphocytes (IEL...

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Main Authors: Emilie H. Regner, Neha Ohri, Andrew Stahly, Mark E. Gerich, Blair P. Fennimore, Diana Ir, Widian K. Jubair, Carsten Görg, Janet Siebert, Charles E. Robertson, Liron Caplan, Daniel N. Frank, Kristine A. Kuhn
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Arthritis Research & Therapy
Subjects:
Inflammatory bowel disease
Ulcerative colitis
Crohn’s disease
Spondyloarthritis
Intraepithelial lymphocytes
Microbiome
Online Access:http://link.springer.com/article/10.1186/s13075-018-1639-3

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