Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs

Osteoporosis, or steroid-induced osteonecrosis of the hip, is accompanied by increased bone marrow adipogenesis. Such a disorder of adipogenic/osteogenic differentiation, affecting bone-marrow-derived mesenchymal stem cells (BMSCs), contributes to bone loss during aging. Here, we investigated the ef...

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Bibliographic Details
Main Authors: Chenglong Wang, Sabine Stöckl, Shushan Li, Marietta Herrmann, Christoph Lukas, Yvonne Reinders, Albert Sickmann, Susanne Grässel
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
extracellular vesicles
mesenchymal stem cells
osteogenic potential
osteogenic differentiation
adipogenic differentiation
ECM remodeling
Online Access:https://www.mdpi.com/2073-4409/11/16/2491

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