A possible role for fumagillin in cellular damage during host infection by Aspergillus fumigatus

A possible role for fumagillin in cellular damage during host infection by Aspergillus fumigatus

Virulence mechanisms of the pathogenic fungus Aspergillus fumigatus are multifactorial and depend on the immune state of the host, but little is known about the fungal mechanism that develops during the process of lung invasion. In this study, microarray technology was combined with a histopathology...

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Bibliographic Details
Main Authors: Xabier Guruceaga, Guillermo Ezpeleta, Emilio Mayayo, Monica Sueiro-Olivares, Ana Abad-Diaz-De-Cerio, José Manuel Aguirre Urízar, Hong G. Liu, Philipp Wiemann, Jin Woo Bok, Scott G. Filler, Nancy P. Keller, Fernando L. Hernando, Andoni Ramirez-Garcia, Aitor Rementeria
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Aspergillus
fumagillin
intranasal infection
AWAFUGE
epithelial cells
cytotoxicity
virulence
Online Access:http://dx.doi.org/10.1080/21505594.2018.1526528

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