A Role for Human Renal Tubular Epithelial Cells in Direct Allo-Recognition by CD4+ T-Cells and the Effect of Ischemia-Reperfusion

A Role for Human Renal Tubular Epithelial Cells in Direct Allo-Recognition by CD4+ T-Cells and the Effect of Ischemia-Reperfusion

Direct allorecognition is the earliest and most potent immune response against a kidney allograft. Currently, it is thought that passenger donor professional antigen-presenting cells (APCs) are responsible. Further, many studies support that graft ischemia-reperfusion injury increases the probabilit...

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Bibliographic Details
Main Authors: Theodoros Eleftheriadis, Georgios Pissas, Marta Crespo, Evdokia Nikolaou, Vassilios Liakopoulos, Ioannis Stefanidis
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
kidney transplantation
renal tubular epithelial cells
direct allorecognition
CD4+ T-cells
ischemia-reperfusion
rejection
Online Access:https://www.mdpi.com/1422-0067/22/4/1733

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