Rare pitfall in the magnetic resonance imaging of status epilepticus
Brain MRI in Status Epilepticus (SE) is often helpful in diagnosis, lateralization and localization of the seizure focus. MRI changes in SE include predominantly ipsilateral diffusion weighted imaging (DWI) changes in the hippocampus and pulvinar or similar changes involving basal ganglia, thalamus,...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-06-01
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| Series: | eNeurologicalSci |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405650222000144 |
| _version_ | 1811336130140831744 |
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| author | Mustafa Al-Chalabi Silvi Bajrami Nurose Karim Ajaz Sheikh |
| author_facet | Mustafa Al-Chalabi Silvi Bajrami Nurose Karim Ajaz Sheikh |
| author_sort | Mustafa Al-Chalabi |
| collection | DOAJ |
| description | Brain MRI in Status Epilepticus (SE) is often helpful in diagnosis, lateralization and localization of the seizure focus. MRI changes in SE include predominantly ipsilateral diffusion weighted imaging (DWI) changes in the hippocampus and pulvinar or similar changes involving basal ganglia, thalamus, cerebellum, brain stem and external capsule (Chatzikonstantinou et al., 2011 [1]). These changes are thought to be due to transient vasogenic and cytotoxic edema due to either transient damage or breakdown of blood brain barrier, proportional to the frequency and duration of the epileptic activity (Amato et al., 2001 [2]). Such changes may also be reflected on T2- weighted and T2-Fluid-Attenuated Inversion Recovery (FLAIR) sequences of MRI.Herein, we present a case of a transient FLAIR cerebrospinal fluid (CSF) hyperintensity on the second MRI brain in a patient with focal status epilepticus. This imaging finding led to diagnostic confusion and was initially thought to represent subarachnoid hemorrhage. However, lumbar puncture, brain computed tomography (CT), and a follow-up brain MRI ruled out that possibility and other CSF pathologies. We concluded that the transient FLAIR changes in the second brain MRI were related to a rare imaging pitfall caused by Gadolinium enhancement of CSF on the FLAIR sequence, popularly referred to as hyperintense acute reperfusion marker (HARM). |
| first_indexed | 2024-04-13T17:34:00Z |
| format | Article |
| id | doaj.art-2f44f0c5dc6c46348ff474c52b713aae |
| institution | Directory Open Access Journal |
| issn | 2405-6502 |
| language | English |
| last_indexed | 2024-04-13T17:34:00Z |
| publishDate | 2022-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | eNeurologicalSci |
| spelling | doaj.art-2f44f0c5dc6c46348ff474c52b713aae2022-12-22T02:37:26ZengElseviereNeurologicalSci2405-65022022-06-0127100405Rare pitfall in the magnetic resonance imaging of status epilepticusMustafa Al-Chalabi0Silvi Bajrami1Nurose Karim2Ajaz Sheikh3Department of Neurology, University of Toledo, Toledo, OH, USA; Corresponding author at: Department of Neurology, University of Toledo, 2130 W Central Ave., Toledo, OH 43606, USA.College of Medicine and Life Sciences, University of Toledo, OH, USADepartment of Neurology, University of Toledo, Toledo, OH, USA; Department of Neurology, University of Toledo, Toledo, OH, USADepartment of Neurology, University of Toledo, Toledo, OH, USABrain MRI in Status Epilepticus (SE) is often helpful in diagnosis, lateralization and localization of the seizure focus. MRI changes in SE include predominantly ipsilateral diffusion weighted imaging (DWI) changes in the hippocampus and pulvinar or similar changes involving basal ganglia, thalamus, cerebellum, brain stem and external capsule (Chatzikonstantinou et al., 2011 [1]). These changes are thought to be due to transient vasogenic and cytotoxic edema due to either transient damage or breakdown of blood brain barrier, proportional to the frequency and duration of the epileptic activity (Amato et al., 2001 [2]). Such changes may also be reflected on T2- weighted and T2-Fluid-Attenuated Inversion Recovery (FLAIR) sequences of MRI.Herein, we present a case of a transient FLAIR cerebrospinal fluid (CSF) hyperintensity on the second MRI brain in a patient with focal status epilepticus. This imaging finding led to diagnostic confusion and was initially thought to represent subarachnoid hemorrhage. However, lumbar puncture, brain computed tomography (CT), and a follow-up brain MRI ruled out that possibility and other CSF pathologies. We concluded that the transient FLAIR changes in the second brain MRI were related to a rare imaging pitfall caused by Gadolinium enhancement of CSF on the FLAIR sequence, popularly referred to as hyperintense acute reperfusion marker (HARM).http://www.sciencedirect.com/science/article/pii/S2405650222000144FLAIRSubarachnoid spaceMRI pitfallStatus EpilepticusHARM |
| spellingShingle | Mustafa Al-Chalabi Silvi Bajrami Nurose Karim Ajaz Sheikh Rare pitfall in the magnetic resonance imaging of status epilepticus eNeurologicalSci FLAIR Subarachnoid space MRI pitfall Status Epilepticus HARM |
| title | Rare pitfall in the magnetic resonance imaging of status epilepticus |
| title_full | Rare pitfall in the magnetic resonance imaging of status epilepticus |
| title_fullStr | Rare pitfall in the magnetic resonance imaging of status epilepticus |
| title_full_unstemmed | Rare pitfall in the magnetic resonance imaging of status epilepticus |
| title_short | Rare pitfall in the magnetic resonance imaging of status epilepticus |
| title_sort | rare pitfall in the magnetic resonance imaging of status epilepticus |
| topic | FLAIR Subarachnoid space MRI pitfall Status Epilepticus HARM |
| url | http://www.sciencedirect.com/science/article/pii/S2405650222000144 |
| work_keys_str_mv | AT mustafaalchalabi rarepitfallinthemagneticresonanceimagingofstatusepilepticus AT silvibajrami rarepitfallinthemagneticresonanceimagingofstatusepilepticus AT nurosekarim rarepitfallinthemagneticresonanceimagingofstatusepilepticus AT ajazsheikh rarepitfallinthemagneticresonanceimagingofstatusepilepticus |