Effects of Microalgae on Metabolic Syndrome
Metabolic syndrome (MetS) is a cluster of metabolic disturbances, including abdominal obesity, hypertension, hypertriglyceridemia, reduced high-density lipoprotein cholesterol (HDL-C) and hyperglycemia. Adopting a healthier lifestyle and multiple drug-based therapies are current ways to manage MetS,...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/12/2/449 |
| _version_ | 1797622688598982656 |
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| author | Kartthigeen Tamel Selvan Jo Aan Goon Suzana Makpol Jen Kit Tan |
| author_facet | Kartthigeen Tamel Selvan Jo Aan Goon Suzana Makpol Jen Kit Tan |
| author_sort | Kartthigeen Tamel Selvan |
| collection | DOAJ |
| description | Metabolic syndrome (MetS) is a cluster of metabolic disturbances, including abdominal obesity, hypertension, hypertriglyceridemia, reduced high-density lipoprotein cholesterol (HDL-C) and hyperglycemia. Adopting a healthier lifestyle and multiple drug-based therapies are current ways to manage MetS, but they have limited efficacy, albeit the prevalence of MetS is rising. Microalgae is a part of the human diet and has also been consumed as a health supplement to improve insulin sensitivity, inflammation, and several components of MetS. These therapeutic effects of microalgae are attributed to the bioactive compounds present in them that exhibit antioxidant, anti-inflammatory, anti-obesity, antihypertensive, hepatoprotective and immunomodulatory effects. Therefore, studies investigating the potential of microalgae in alleviating MetS are becoming more popular, but a review on this topic remains scarce. In this review, we discuss the effects of microalgae, specifically on MetS, by reviewing the evidence from scientific literature covering in vitro and in vivo studies. In addition, we also discuss the underlying mechanisms that modulate the effects of microalgae on MetS, and the limitations and future perspectives of developing microalgae as a health supplement for MetS. Microalgae supplementation is becoming a viable approach in alleviating metabolic disturbances and as a unique addition to the management of MetS. |
| first_indexed | 2024-03-11T09:13:49Z |
| format | Article |
| id | doaj.art-2f48c70dd09649af8f6500698d3fbe8b |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-11T09:13:49Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-2f48c70dd09649af8f6500698d3fbe8b2023-11-16T18:48:25ZengMDPI AGAntioxidants2076-39212023-02-0112244910.3390/antiox12020449Effects of Microalgae on Metabolic SyndromeKartthigeen Tamel Selvan0Jo Aan Goon1Suzana Makpol2Jen Kit Tan3Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Jalan Ya’acob Latiff, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, MalaysiaDepartment of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Jalan Ya’acob Latiff, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, MalaysiaDepartment of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Jalan Ya’acob Latiff, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, MalaysiaDepartment of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia (UKM), Jalan Ya’acob Latiff, Bandar Tun Razak, Cheras, Kuala Lumpur 56000, MalaysiaMetabolic syndrome (MetS) is a cluster of metabolic disturbances, including abdominal obesity, hypertension, hypertriglyceridemia, reduced high-density lipoprotein cholesterol (HDL-C) and hyperglycemia. Adopting a healthier lifestyle and multiple drug-based therapies are current ways to manage MetS, but they have limited efficacy, albeit the prevalence of MetS is rising. Microalgae is a part of the human diet and has also been consumed as a health supplement to improve insulin sensitivity, inflammation, and several components of MetS. These therapeutic effects of microalgae are attributed to the bioactive compounds present in them that exhibit antioxidant, anti-inflammatory, anti-obesity, antihypertensive, hepatoprotective and immunomodulatory effects. Therefore, studies investigating the potential of microalgae in alleviating MetS are becoming more popular, but a review on this topic remains scarce. In this review, we discuss the effects of microalgae, specifically on MetS, by reviewing the evidence from scientific literature covering in vitro and in vivo studies. In addition, we also discuss the underlying mechanisms that modulate the effects of microalgae on MetS, and the limitations and future perspectives of developing microalgae as a health supplement for MetS. Microalgae supplementation is becoming a viable approach in alleviating metabolic disturbances and as a unique addition to the management of MetS.https://www.mdpi.com/2076-3921/12/2/449microalgaemetabolic syndromeobesityhypertensionhypertriglyceridemiahigh-density lipoprotein cholesterol |
| spellingShingle | Kartthigeen Tamel Selvan Jo Aan Goon Suzana Makpol Jen Kit Tan Effects of Microalgae on Metabolic Syndrome Antioxidants microalgae metabolic syndrome obesity hypertension hypertriglyceridemia high-density lipoprotein cholesterol |
| title | Effects of Microalgae on Metabolic Syndrome |
| title_full | Effects of Microalgae on Metabolic Syndrome |
| title_fullStr | Effects of Microalgae on Metabolic Syndrome |
| title_full_unstemmed | Effects of Microalgae on Metabolic Syndrome |
| title_short | Effects of Microalgae on Metabolic Syndrome |
| title_sort | effects of microalgae on metabolic syndrome |
| topic | microalgae metabolic syndrome obesity hypertension hypertriglyceridemia high-density lipoprotein cholesterol |
| url | https://www.mdpi.com/2076-3921/12/2/449 |
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