Nootkatone Supplementation Ameliorates Carbon Tetrachloride-Induced Acute Liver Injury via the Inhibition of Oxidative Stress, NF-κB Pathways, and the Activation of Nrf2/HO-1 Pathway

Nootkatone Supplementation Ameliorates Carbon Tetrachloride-Induced Acute Liver Injury via the Inhibition of Oxidative Stress, NF-κB Pathways, and the Activation of Nrf2/HO-1 Pathway

Acute liver injury is a type of liver diseases, and it has raised concerns worldwide due to the lack of effective therapies. The aim of this study is to investigate the protective effects of nootkatone (NOOT) on carbon tetrachloride (CCl<sub>4</sub>)-caused acute liver injury in mice. Mi...

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Bibliographic Details
Main Authors: Chongshan Dai, Xueyong Zhang, Jiahao Lin, Jianzhong Shen
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Antioxidants
Subjects:
nootkatone
oxidative stress
acute liver injury
Nrf2/HO-1 pathway
NF-κB pathway
Online Access:https://www.mdpi.com/2076-3921/12/1/194

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https://www.mdpi.com/2076-3921/12/1/194

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