Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions
Objective: To evaluate the impact of adding 3D Tomosynthesis to Full Field Digital Mammography (FFDM) in the detection and diagnosis of breast lesions. Subjects and methods: The study included 166 mammograms with indeterminate findings selected from 1600 mammograms. They were classified into two gro...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2014-09-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X14000539 |
| _version_ | 1818190238292377600 |
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| author | Sahar Mansour Lamia Adel Omina Mokhtar Omar Sherif Omar |
| author_facet | Sahar Mansour Lamia Adel Omina Mokhtar Omar Sherif Omar |
| author_sort | Sahar Mansour |
| collection | DOAJ |
| description | Objective: To evaluate the impact of adding 3D Tomosynthesis to Full Field Digital Mammography (FFDM) in the detection and diagnosis of breast lesions.
Subjects and methods: The study included 166 mammograms with indeterminate findings selected from 1600 mammograms. They were classified into two groups: group 1 ‘Diagnostic mammograms’ of symptomatic women and group 2 ‘Screening mammograms’. Dense breasts assigned as ACR3 and ACR4 presented 69% (n = 114/166) of the studied cases. FFDM and 3D tomosynthesis examination was done and imaging findings were evaluated before and after the use of 3D tomosynthesis images.
Results: Both modalities were compared regarding detection and diagnosis, each individually assessed, using the Pearson Chi Square tests. Detection (P value: 0.006) and diagnosis (P value: 0.048) of breast lesions dramatically improved when 3D tomosynthesis images were considered in the evaluation. The sensitivity, specificity, and accuracy of digital mammography was 60%, 20.7% and 48% have significantly enhanced on applying tomosynthesis to be 94.5%, 74% and 89.7%.
Conclusion: Three-dimensional tomosynthesis significantly enhanced the detection and characterization of breast lesions on digital mammography especially in the context of dense breast parenchyma (ACR 3&4). |
| first_indexed | 2024-12-11T23:55:32Z |
| format | Article |
| id | doaj.art-2f49c354b79c443bbf4a1e01024f4318 |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-11T23:55:32Z |
| publishDate | 2014-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-2f49c354b79c443bbf4a1e01024f43182022-12-22T00:45:22ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2014-09-014531053106110.1016/j.ejrnm.2014.03.007Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesionsSahar Mansour0Lamia Adel1Omina Mokhtar2Omar Sherif Omar3Radiology Department (Women’s Imaging Unit), Faculty of Medicine, Cairo University, EgyptRadiology Department (Women’s Imaging Unit), Faculty of Medicine, Cairo University, EgyptRadiology Department (Women’s Imaging Unit), National Cancer Institute of Cairo, EgyptSurgery Department (Breast Specialist), Faculty of Medicine, Cairo University, EgyptObjective: To evaluate the impact of adding 3D Tomosynthesis to Full Field Digital Mammography (FFDM) in the detection and diagnosis of breast lesions. Subjects and methods: The study included 166 mammograms with indeterminate findings selected from 1600 mammograms. They were classified into two groups: group 1 ‘Diagnostic mammograms’ of symptomatic women and group 2 ‘Screening mammograms’. Dense breasts assigned as ACR3 and ACR4 presented 69% (n = 114/166) of the studied cases. FFDM and 3D tomosynthesis examination was done and imaging findings were evaluated before and after the use of 3D tomosynthesis images. Results: Both modalities were compared regarding detection and diagnosis, each individually assessed, using the Pearson Chi Square tests. Detection (P value: 0.006) and diagnosis (P value: 0.048) of breast lesions dramatically improved when 3D tomosynthesis images were considered in the evaluation. The sensitivity, specificity, and accuracy of digital mammography was 60%, 20.7% and 48% have significantly enhanced on applying tomosynthesis to be 94.5%, 74% and 89.7%. Conclusion: Three-dimensional tomosynthesis significantly enhanced the detection and characterization of breast lesions on digital mammography especially in the context of dense breast parenchyma (ACR 3&4).http://www.sciencedirect.com/science/article/pii/S0378603X14000539BreastDigital mammographyBiopsyComputer applications-3DCalcifications |
| spellingShingle | Sahar Mansour Lamia Adel Omina Mokhtar Omar Sherif Omar Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions The Egyptian Journal of Radiology and Nuclear Medicine Breast Digital mammography Biopsy Computer applications-3D Calcifications |
| title | Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions |
| title_full | Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions |
| title_fullStr | Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions |
| title_full_unstemmed | Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions |
| title_short | Comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions |
| title_sort | comparative study between breast tomosynthesis and classic digital mammography in the evaluation of different breast lesions |
| topic | Breast Digital mammography Biopsy Computer applications-3D Calcifications |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X14000539 |
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