Akt1 genetic variants confer increased susceptibility to thyroid cancer

Akt1 genetic variants confer increased susceptibility to thyroid cancer

The PI3K-Akt-mTOR pathway plays a central role in the development of non-medullary thyroid carcinoma (NMTC). Although somatic mutations have been identified in these genes in NMTC patients, the role of germline variants has not been investigated. Here, we selected frequently occurring genetic varian...

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Bibliographic Details
Main Authors:	Thomas Crezee, Mirela Petrulea, Doina Piciu, Martin Jaeger, Jan W A Smit, Theo S Plantinga, Carmen E Georgescu, Romana Netea-Maier
Format:	Article
Language:	English
Published:	Bioscientifica 2020-12-01
Series:	Endocrine Connections
Subjects:	non-medullary thyroid cancer susceptibility pi3k/akt/mtor genetic variation
Online Access:	https://ec.bioscientifica.com/view/journals/ec/9/11/EC-20-0311.xml

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