The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery

Emergence agitation (EA) is one of the main concerns in the field of pediatric anesthesia using sevoflurane. We investigated the effects of remifentanil and fentanyl on the incidence of EA in pediatric patients undergoing strabismus surgery. Ninety children were randomly allocated into two groups an...

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Main Authors: Jongyoon Baek, Sang Jin Park, Jun Oh Kim, Minhyun Kim, Do Young Kim, Eun Kyung Choi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/9/5/606
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author Jongyoon Baek
Sang Jin Park
Jun Oh Kim
Minhyun Kim
Do Young Kim
Eun Kyung Choi
author_facet Jongyoon Baek
Sang Jin Park
Jun Oh Kim
Minhyun Kim
Do Young Kim
Eun Kyung Choi
author_sort Jongyoon Baek
collection DOAJ
description Emergence agitation (EA) is one of the main concerns in the field of pediatric anesthesia using sevoflurane. We investigated the effects of remifentanil and fentanyl on the incidence of EA in pediatric patients undergoing strabismus surgery. Ninety children were randomly allocated into two groups and received either remifentanil (group R: intraoperatively remifentanil 0.2 μg/kg/min) or fentanyl (group F: fentanyl 2 μg/kg at anesthetic induction) intraoperatively. After surgery, EA incidence was assessed using a four-point agitation scale and Pediatric Anesthesia Emergence Delirium (PAED) scale in the post-anesthesia care unit. Face, leg, activity, cry, and consolability (FLACC) scores for postoperative pain were also assessed. The incidence of EA using the four-point agitation scale (scores ≥ 3) was similar in both groups (remifentanil group, 28.89% vs. fentanyl group, 24.44%). Similar results were obtained using the PAED scale (scores > 12), with an incidence of 33.33% in the remifentanil group and 26.67% in the fentanyl group. Differences in FLACC scores were not found to be statistically significant. A single bolus administration of fentanyl during anesthetic induction and continuous infusion of remifentanil during surgery had similar effects on the EA incidence in these pediatric patients.
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spelling doaj.art-2f4b14e9dad848fb83d52cd3f0faf8ea2023-11-23T10:29:45ZengMDPI AGChildren2227-90672022-04-019560610.3390/children9050606The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus SurgeryJongyoon Baek0Sang Jin Park1Jun Oh Kim2Minhyun Kim3Do Young Kim4Eun Kyung Choi5Department of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, KoreaDepartment of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, KoreaDepartment of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, KoreaDepartment of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, KoreaDepartment of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, KoreaDepartment of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, KoreaEmergence agitation (EA) is one of the main concerns in the field of pediatric anesthesia using sevoflurane. We investigated the effects of remifentanil and fentanyl on the incidence of EA in pediatric patients undergoing strabismus surgery. Ninety children were randomly allocated into two groups and received either remifentanil (group R: intraoperatively remifentanil 0.2 μg/kg/min) or fentanyl (group F: fentanyl 2 μg/kg at anesthetic induction) intraoperatively. After surgery, EA incidence was assessed using a four-point agitation scale and Pediatric Anesthesia Emergence Delirium (PAED) scale in the post-anesthesia care unit. Face, leg, activity, cry, and consolability (FLACC) scores for postoperative pain were also assessed. The incidence of EA using the four-point agitation scale (scores ≥ 3) was similar in both groups (remifentanil group, 28.89% vs. fentanyl group, 24.44%). Similar results were obtained using the PAED scale (scores > 12), with an incidence of 33.33% in the remifentanil group and 26.67% in the fentanyl group. Differences in FLACC scores were not found to be statistically significant. A single bolus administration of fentanyl during anesthetic induction and continuous infusion of remifentanil during surgery had similar effects on the EA incidence in these pediatric patients.https://www.mdpi.com/2227-9067/9/5/606emergence agitationsevofluraneremifentanilfentanylanesthesia
spellingShingle Jongyoon Baek
Sang Jin Park
Jun Oh Kim
Minhyun Kim
Do Young Kim
Eun Kyung Choi
The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery
Children
emergence agitation
sevoflurane
remifentanil
fentanyl
anesthesia
title The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery
title_full The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery
title_fullStr The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery
title_full_unstemmed The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery
title_short The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery
title_sort effects of remifentanil and fentanyl on emergence agitation in pediatric strabismus surgery
topic emergence agitation
sevoflurane
remifentanil
fentanyl
anesthesia
url https://www.mdpi.com/2227-9067/9/5/606
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